DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE9 and Vars1

DIOPT Version :9

Sequence 1:	NP_725784.1	Gene:	GstE9 / 246581	FlyBaseID:	FBgn0063491	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_445744.1	Gene:	Vars1 / 25009	RGDID:	3950	Length:	1264	Species:	Rattus norvegicus

Alignment Length:	185	Identity:	40/185 - (21%)
Similarity:	77/185 - (41%)	Gaps:	29/185 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 PQHTVPVLED--DGKFIWESHAICAYLVRRYAKSDDLYPKDY----FKRA--LVDQRLHFESGVL 107
            |...:|.||.  .|.::|.:.|:...          |:|...    ..||  ||.|.:.:....|
  Rat    53 PPPRLPALEQGPGGLWVWGAPAVAQL----------LWPAGLGGPGGSRAAVLVQQWVSYADTEL 107

  Fly   108 FQGCIRNIAIPLFYKNITEVPRSQIDAIYEAYDFLEAFIGNQAYLCGPVITIADYSVVSSVSSLV 172
            ...........|..:...:.|::.:.|:.:|.:.||.::....||.|...|:||.:.|:::  |:
  Rat   108 TPAACGATLPALGLRGPGQDPQAALGALGKALNPLEEWLRLHTYLAGDAPTLADLAAVTAL--LL 170

  Fly   173 GLAAI---DAKR-YPKLNGWLDRMAAQPNYQSLNG-----NGAQMLIDMFSSKIT 218
            ....:   .|:| :..:..|.:....||.::::.|     :||:.:.....|:||
  Rat   171 PFRYVLDPSARRIWGNVTRWFNTCVRQPEFRAVLGEVVLYSGARSVTQQPGSEIT 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE9	NP_725784.1	GstA	4..201	CDD:223698	34/161 (21%)
		GST_N_Delta_Epsilon	4..76	CDD:239343	7/26 (27%)
		GST_C_Delta_Epsilon	92..209	CDD:198287	28/127 (22%)
Vars1	NP_445744.1	GstA	<56..203	CDD:223698	33/158 (21%)
		GST_C_family	92..213	CDD:295467	25/122 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..296		3/8 (38%)
		PTZ00419	282..1264	CDD:240411
		ValRS_core	335..938	CDD:185677
		'HIGH' region	344..354
		tRNA-synt_1_2	513..640	CDD:290334
		'KMSKS' region	862..866
		Anticodon_Ia_Val	938..1075	CDD:153416
		Val_tRNA-synt_C	1196..1258	CDD:287436
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810