DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE9 and Vars

DIOPT Version :9

Sequence 1:	NP_725784.1	Gene:	GstE9 / 246581	FlyBaseID:	FBgn0063491	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_035820.3	Gene:	Vars / 22321	MGIID:	90675	Length:	1263	Species:	Mus musculus

Alignment Length:	184	Identity:	38/184 - (20%)
Similarity:	76/184 - (41%)	Gaps:	29/184 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 PQHTVPVLED--DGKFIWESHAICAYLVRRYAKSDDLYPKDY----FKRA--LVDQRLHFESGVL 107
            |...:|.||.  .|.::|.:.|:...          |:|...    ..||  ||.|.:.:....|
Mouse    53 PPPRLPALEQGPGGLWVWGAPAVAQL----------LWPAGLGGPGGSRAAVLVQQWVSYADTEL 107

  Fly   108 FQGCIRNIAIPLFYKNITEVPRSQIDAIYEAYDFLEAFIGNQAYLCGPVITIADYSVVSSVSSLV 172
            ...........|..:...:.|::.:.|:.:|.:.||.::....||.|...|:||.:.|:::  |:
Mouse   108 IPAACGATLPALGLRGPGQDPQAALGALGKALNPLEDWLRLHTYLAGDAPTLADLAAVTAL--LL 170

  Fly   173 GLAAI---DAKR-YPKLNGWLDRMAAQPNYQSLNG-----NGAQMLIDMFSSKI 217
            ....:   .|:| :..:..|.:....||.::::.|     :||:.:.....|::
Mouse   171 PFRYVLDPSARRIWGNVTRWFNTCVRQPEFRAVLGEVALYSGARSVTQQPGSEV 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE9	NP_725784.1	GstA	4..201	CDD:223698	34/161 (21%)
		GST_N_Delta_Epsilon	4..76	CDD:239343	7/26 (27%)
		GST_C_Delta_Epsilon	92..209	CDD:198287	28/127 (22%)
Vars	NP_035820.3	GST_C_family	92..213	CDD:383119	25/122 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..294		1/7 (14%)
		PTZ00419	281..1263	CDD:240411
		'HIGH' region	343..353
		'KMSKS' region	861..865
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810