DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstE9 and CLIC2

DIOPT Version :9

Sequence 1:NP_725784.1 Gene:GstE9 / 246581 FlyBaseID:FBgn0063491 Length:221 Species:Drosophila melanogaster
Sequence 2:NP_001280.3 Gene:CLIC2 / 1193 HGNCID:2063 Length:247 Species:Homo sapiens


Alignment Length:117 Identity:25/117 - (21%)
Similarity:49/117 - (41%) Gaps:25/117 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 YLVRRYAKSDD----LYPK--DYFKRALVDQRLHFESGVL--FQGCIRNIAIPLFYKNITEVPRS 130
            :|..:|.:|.|    |:.|  .|.|....:...:||..:|  |:.....:..||    :.|:...
Human   101 HLSPKYKESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPL----LDEIDPD 161

  Fly   131 QIDAIYEAYDFLEAFIGNQAYLCGPVITIADYSVVSSVSSLVGLAAIDAKRY 182
            ..:         |..:..:.:|.|..:|:||.|::..::    :..:.||:|
Human   162 SAE---------EPPVSRRLFLDGDQLTLADCSLLPKLN----IIKVAAKKY 200

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstE9NP_725784.1 GstA 4..201 CDD:223698 25/117 (21%)
GST_N_Delta_Epsilon 4..76 CDD:239343 0/1 (0%)
GST_C_Delta_Epsilon 92..209 CDD:198287 18/93 (19%)
CLIC2NP_001280.3 Required for insertion into the membrane. /evidence=ECO:0000250 1..96
N-terminal 1..94
O-ClC 12..245 CDD:129941 25/117 (21%)
Joint loop 95..106 1/4 (25%)
C-terminal 107..247 23/111 (21%)
Foot loop 151..171 4/32 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154405
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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