DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstE9 and Clic1

DIOPT Version :10

Sequence 1:NP_725784.1 Gene:GstE9 / 246581 FlyBaseID:FBgn0063491 Length:221 Species:Drosophila melanogaster
Sequence 2:NP_254279.1 Gene:Clic1 / 114584 MGIID:2148924 Length:241 Species:Mus musculus


Alignment Length:171 Identity:35/171 - (20%)
Similarity:57/171 - (33%) Gaps:42/171 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 GKL--VLYGVEASPPVRACKLTLDALGLQYEYRLVNLLAGEHKTKEFSLKNPQHTVPVLEDDGKF 64
            |:|  :|||.|........:..|:|:.....|            .:.:..||:.....|:...||
Mouse    62 GQLPFLLYGTEVHTDTNKIEEFLEAMLCPPRY------------PKLAALNPESNTSGLDIFAKF 114

  Fly    65 IWESHAICAYLVRRYAKSDDLYPKDYFKRAL--------------VDQRLHFESGVLFQGCIRNI 115
                   .||:.......:|...|...| ||              ||:....:.|:..:..:...
Mouse   115 -------SAYIKNSNPALNDNLEKGLLK-ALKVLDNYLTSPLPEEVDETSAEDEGISQRKFLDGN 171

  Fly   116 AIPLFYKNITEVPRSQIDAI----YEAYDFLEAFIGNQAYL 152
            .:.|...|:  :|:..|..:    |..:...|||.|...||
Mouse   172 ELTLADCNL--LPKLHIVQVVCKKYRGFTIPEAFRGVHRYL 210

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstE9NP_725784.1 GstA 4..199 CDD:440390 34/169 (20%)
Clic1NP_254279.1 Required for insertion into the membrane. /evidence=ECO:0000250 2..90 8/27 (30%)
O-ClC 6..241 CDD:129941 35/171 (20%)
G-site. /evidence=ECO:0000250|UniProtKB:O00299 24..27
Blue background indicates that the domain is not in the aligned region.

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