DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30378 and CALML4

DIOPT Version :10

Sequence 1:NP_724628.1 Gene:CG30378 / 246577 FlyBaseID:FBgn0050378 Length:148 Species:Drosophila melanogaster
Sequence 2:NP_219501.3 Gene:CALML4 / 91860 HGNCID:18445 Length:153 Species:Homo sapiens


Alignment Length:219 Identity:46/219 - (21%)
Similarity:68/219 - (31%) Gaps:81/219 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    76 PIVWTLRDRKIFNRRIKHAAA---KQNMNLRDIRLHNYPQLKLD-H--IVKERYPTFIDAIKELD 134
            |:.:.|....||...|..|..   .:.|..|:...|:.....:| |  :.|||...|.|.:..: 
Human   205 PLSYLLMVTVIFLPHISKATTWCKDKLMGQRESPAHDMEPFSIDLHAPLSKERVEAFSDGVYAI- 268

  Fly   135 DCMTLLFM---FSTFPATKIITRELTRMSRRLTVEFMHYVIAAQALRKVFISIKGYYFQAEIKGE 196
             ..|||.:   ....|..|.:..           :|...::||          .|.|        
Human   269 -VATLLILDICEDNVPDPKDVQE-----------KFSGSLVAA----------LGAY-------- 303

  Fly   197 TVTWIVPHYFPYSPHRGEMVDLSIMKSFGDFFTVMAGFINYRLYHSINLVYPPQFAHSLDSDETM 261
                 .|.:..|               ||.|.||  |.: :..:||:       |.|...:.:||
Human   304 -----GPQFLAY---------------FGSFATV--GLL-WFAHHSL-------FLHVRKATQTM 338

  Fly   262 GNEQKFVSERIAALNVELLRSDGG 285
            |           .||:..|...||
Human   339 G-----------LLNILSLAFVGG 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30378NP_724628.1 PTZ00184 1..148 CDD:185504 19/80 (24%)
CALML4NP_219501.3 PTZ00184 1..143 CDD:185504
Blue background indicates that the domain is not in the aligned region.

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