DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30375 and Hgfac

DIOPT Version :9

Sequence 1:	NP_724665.1	Gene:	CG30375 / 246575	FlyBaseID:	FBgn0050375	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	XP_006504094.1	Gene:	Hgfac / 54426	MGIID:	1859281	Length:	658	Species:	Mus musculus

Alignment Length:	422	Identity:	96/422 - (22%)
Similarity:	174/422 - (41%)	Gaps:	94/422 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SCAQQQCTRFFDLIPNRTI---NITSF-NYPGAIPSGSNCRFRLKAPSNHVIYLS---------- 68
            :|......||.:::|....   |.|.: .......||.:|    .|.::.::|..
Mouse   265 TCPLGYAGRFCNIVPTEHCFLGNGTEYRGVASTAASGLSC----LAWNSDLLYQELHVDSVAAAV 325

  Fly    69 ---------CRFELFPDTCGSEFLFISRDGDLQFRDGERYCRMGQVNRISNFQTMAFAYYSSSPQ 124
                     ||   .||.....:.::.:|..|.:    .|||:.....::...:......::.|:
Mouse   326 LLGLGPHAYCR---NPDKDERPWCYVVKDNALSW----EYCRLTACESLARVHSQTPEILAALPE 383

  Fly   125 TQQRSRLNC------QAVARPAPCDCGWSFPNRIANGVEA--GKHEFPSMVGLRDLSSNLPIFCG 181
            :....|..|      :...||           ||..|..:  |.|.:.:.:.:.:      .||.
Mouse   384 SAPAVRPTCGKRHKKRTFLRP-----------RIIGGSSSLPGSHPWLAAIYIGN------SFCA 431

  Fly   182 GSIVSERYIMTAAHCTARQPVASRLLALVGEH--DLSTGAESIYAAQ----YRIQNIINHPGYME 240
            ||:|...::::||||.|..|....:..::|:|  :.:|.....:..:    |.:.::.|
Mouse   432 GSLVHTCWVVSAAHCFANSPPRDSITVVLGQHFFNRTTDVTQTFGIEKYVPYTLYSVFN------ 490

  Fly   241 TASGNINDIALLQTATPIE----WSRGVAPICLPIRQAENSF-NYQNVDIMGWGTLG------FA 294
               .|.:|:.|::.....|    .|:.|.|||||  :|.:|| ......|.|||.:.      ..
Mouse   491 ---PNNHDLVLIRLKKKGERCAVRSQFVQPICLP--EAGSSFPTGHKCQIAGWGHMDEMQSSTDV 550

  Fly   295 ASKSNTLQKATLLTMDNAVCRSR--FNSSITPSHLCT--YDAGGRGQDSCQYDSGGPVILRQRER 355
            :|.||:|.:|.:..:.:..|.|.  :.:.|:|:.||.  :|.   ..|:||.|||||::..:...
Mouse   551 SSYSNSLLEALVPLVADHKCSSPEVYGADISPNMLCAGYFDC---KSDACQGDSGGPLVCEKNGV 612

  Fly   356 MFQLGVISYGRACGQPFGIGVNTRVTSHLNWL 387
            .:..|:||:|..||:....||.|||.::::|:
Mouse   613 AYLYGIISWGDGCGRLNKPGVYTRVANYVDWI 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30375	NP_724665.1	CUB	38..>100	CDD:294042	12/81 (15%)
		Tryp_SPc	151..386	CDD:214473	70/257 (27%)
		Tryp_SPc	152..387	CDD:238113	69/257 (27%)
Hgfac	XP_006504094.1	FN2	99..145	CDD:128373
		EGF_CA	159..194	CDD:238011
		FN1	197..237	CDD:238018
		EGF_CA	242..275	CDD:238011	2/9 (22%)
		Kringle	283..364	CDD:333799	16/91 (18%)
		Tryp_SPc	406..646	CDD:238113	70/259 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000