DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30375 and CG12951

DIOPT Version :9

Sequence 1:	NP_724665.1	Gene:	CG30375 / 246575	FlyBaseID:	FBgn0050375	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_649880.1	Gene:	CG12951 / 41110	FlyBaseID:	FBgn0037677	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	245	Identity:	79/245 - (32%)
Similarity:	125/245 - (51%)	Gaps:	22/245 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 NRIANGVEAGKHEFPSMVGLRDLSSNLPIFCGGSIVSERYIMTAAHCTARQPVASRLLALVGEHD 214
            :|:.||.::...::|.:|.||....:..  |||||:|:.::|||||||..:| |..|....|..:
  Fly    28 SRVVNGTDSSVLKYPFVVSLRSYDGSHS--CGGSIISKHFVMTAAHCTNGRP-ADTLSIQFGVTN 89

  Fly   215 LSTGAESIYAAQYRIQNIINHPGYMETASGNINDIALLQTATPIEWSR-GVAPICLP---IRQAE 275
            :|....::..    |:.||.|..:..|.. |.|||:||....|.|:.. .|||:.||   ....:
  Fly    90 ISAMGPNVVG----IKKIIQHEDFDPTRQ-NANDISLLMVEEPFEFDGVSVAPVELPALAFAVPQ 149

  Fly   276 NSFNYQNVDIMGWGTLGFAASKSNTLQKATLLTMDNAVCRSRFNSSITPS-HLC-TYDAGGRGQD 338
            :....:.| ::|||......|..:|||:.:|....:..|.||.|....|. |:| ..|.||:||
  Fly   150 SDAGVEGV-LIGWGLNDTYGSVQDTLQEVSLKIYSDEECTSRHNGQTDPKYHICGGVDEGGKGQ- 212

  Fly   339 SCQYDSGGPVILRQRERMFQLGVISYG-RACGQPFGIGVNTRVTSHLNWL 387
             |..|||||:|...:    |:|::|:. :.|......||..:|:.:::|:
  Fly   213 -CSGDSGGPLIYNGQ----QVGIVSWSIKPCTVAPYPGVYCKVSQYVDWI 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30375	NP_724665.1	CUB	38..>100	CDD:294042
		Tryp_SPc	151..386	CDD:214473	78/241 (32%)
		Tryp_SPc	152..387	CDD:238113	77/241 (32%)
CG12951	NP_649880.1	Tryp_SPc	29..257	CDD:214473	78/242 (32%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	78/243 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456018
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930