DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30375 and Ser7

DIOPT Version :9

Sequence 1:	NP_724665.1	Gene:	CG30375 / 246575	FlyBaseID:	FBgn0050375	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster

Alignment Length:	326	Identity:	99/326 - (30%)
Similarity:	143/326 - (43%)	Gaps:	68/326 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 RISNFQTMAFAYYSSS-------PQTQQRSRLNCQAVARPAPCD-------CGWSFPNRIANGVE 157
            ||||..|.|    :||       |:|..|.         |:..|       ||.:|..|:..|..
  Fly    86 RISNGTTNA----TSSTTTLKLLPRTTPRP---------PSGIDQLPEHPYCGSAFSFRLVGGHN 137

  Fly   158 AGKHEFP--SMVGLRDLSSNLPIFCGGSIVSERYIMTAAHC---TARQPVASRLLALVGEHDLST 217
            .|..|||  :::....:|......||.|.:::|:::|||||   ..|...|    |::||.:..|
  Fly   138 TGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTA----AILGEWNRDT 198

  Fly   218 ---------GAESIYAAQYR--IQNIINHPGYMETASGNINDIALLQTATPIEW--SRGVAPICL 269
                     |.........|  |..|:.|..|.|.  ...||||||:.:.|:.|  .:.:.|:||
  Fly   199 DPDCENDLNGVRECAPPHIRVTIDRILPHAQYSEL--NYRNDIALLRLSRPVNWLQMQNLEPVCL 261

  Fly   270 PIRQAE--NSFNYQNVDIMGWGTLGFAASKSNTLQKATLLTMDNAVCRSRF--NSSIT--PSHLC 328
            |.::..  |.......|:.|||....:.| |...|||.|.......|:..|  ::.||  .|.:|
  Fly   262 PPQRGRYANQLAGSAADVSGWGKTESSGS-SKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMC 325

  Fly   329 TYDAGGR-GQDSCQYDSGGPVILRQ-----RERMFQLGVISYGRA-CGQPFGIGVNTRVTSHLNW 386
               |||. |.|||..|||||:.:..     ...::..||:|.||. ||.....|:.|||:|:::|
  Fly   326 ---AGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDW 387

  Fly   387 L 387
            :
  Fly   388 I 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30375	NP_724665.1	CUB	38..>100	CDD:294042
		Tryp_SPc	151..386	CDD:214473	82/265 (31%)
		Tryp_SPc	152..387	CDD:238113	81/265 (31%)
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	82/266 (31%)
		Tryp_SPc	133..391	CDD:238113	82/266 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455915
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030