DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment swif and cola

DIOPT Version :9

Sequence 1:NP_001097231.1 Gene:swif / 246569 FlyBaseID:FBgn0050366 Length:284 Species:Drosophila melanogaster
Sequence 2:NP_724673.1 Gene:cola / 246566 FlyBaseID:FBgn0050363 Length:259 Species:Drosophila melanogaster


Alignment Length:217 Identity:62/217 - (28%)
Similarity:84/217 - (38%) Gaps:65/217 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    81 KCCVLR----SAAK------------NPCVEIRRPKAAKLEEKPFRSMWEPPCKANEQPFCKEML 129
            :||.:|    :|.|            |.|.|  :|..|..|...:  :.|...:....|.|...|
  Fly    34 ECCKMRDKDTTACKDGKWFCPVKYEPNKCYE--KPSFAVEEYSQY--LQEIYNRGKTNPDCLLKL 94

  Fly   130 PRFDAMYYHPSNKCRCYQRTWVECSPVKKRLKKVCCLDAIEPPEILY-----RIRPPCPGTCQIN 189
            .|.||.:|.||:|.|.:||||.||..:..|.|..||     |.:.:|     |||||        
  Fly    95 IRHDAEHYKPSDKQRKFQRTWPECPLLWLRPKDYCC-----PDQEVYQPMNRRIRPP-------- 146

  Fly   190 YKARRLLCADGEWERDPTRK------------CPKFFHPCCKLARCNPRCSRGRKPTLCTKLRAP 242
                          ::|...            |.....||||:.|..|:|::.|:|:.|.|...|
  Fly   147 --------------QEPPLSAIEKHLFQMSIFCKSVRAPCCKVGRRPPKCTKPRRPSECCKKFTP 197

  Fly   243 YPCYSEKIRGTRP-LRKRECLC 263
            .|.:||..|...| ....||.|
  Fly   198 MPSFSEACRHLIPRFCGSECAC 219

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
swifNP_001097231.1 DUF1431 121..278 CDD:284625 50/161 (31%)
colaNP_724673.1 DM6 84..232 CDD:214775 50/163 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45451811
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_2FCF2
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0005300
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR20977
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
43.930

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