DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30350 and CPR3

DIOPT Version :9

Sequence 1:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_013633.1	Gene:	CPR3 / 854897	SGDID:	S000004543	Length:	182	Species:	Saccharomyces cerevisiae

Alignment Length:	191	Identity:	45/191 - (23%)
Similarity:	75/191 - (39%)	Gaps:	35/191 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 KSDAELRRLFR-------PRIYFDLYLKDARPLGRFVVQLYTEAAPLVVLQLIKSCMCNQHSKFM 259
            :|..:..|||.       .:::||..:...: :||...:||....|......  ..:|.....:.
Yeast     4 RSIIQQSRLFSNSASRLGKKVFFDPAVNGTK-IGRIEFELYDNVVPKTAENF--RALCTGEKGWG 65

  Fly   260 VK-----RLFPNLWL---ETDLM--LSSDSLLHQPLEYDAKVIDHGASSYVLSFSKAYVTGF--- 311
            .|     |:.|:..:   :|||.  ....|:      |.:|..|   .::|....||.:...
Yeast    66 YKGVPFHRIIPDFMIQGGDTDLTNGFGGKSI------YGSKFAD---ENFVKKHDKAGLLSMANA 121

  Fly   312 ---THHLSFAISFKPLTVVNGSRVGFGRIVKGSKICECIQSYGTKNGKLSRGLLFTSCGLL 369
               |:...|.|:..|...::|..|.||.:.||..|.:.|:||||.:||....::....|.|
Yeast   122 GPNTNGSQFFITTVPCPWLDGKHVVFGEVTKGMDIVKAIESYGTASGKPRAEIVIEEAGEL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	40/179 (22%)
CPR3	NP_013633.1	cyclophilin_ABH_like	23..180	CDD:238907	39/168 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810