DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30350 and CPR6

DIOPT Version :9

Sequence 1:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_013317.1	Gene:	CPR6 / 850914	SGDID:	S000004206	Length:	371	Species:	Saccharomyces cerevisiae

Alignment Length:	186	Identity:	45/186 - (24%)
Similarity:	74/186 - (39%)	Gaps:	41/186 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 RPRIYFDLYLKDARPLGRFVVQLYTEAAPLVVLQLIKSCMCNQHSKFMVKRLFPNLWLETDLMLS 276
            ||:.:||:.: ..:|.||.|.:||.:..|......:|.|..|..   |.|       .:.|:.||
Yeast     3 RPKTFFDISI-GGKPQGRIVFELYNDIVPKTAENFLKLCEGNAG---MAK-------TKPDVPLS 56

  Fly   277 -SDSLLHQPLE--------------------YDAKVIDHGAS-----SYVLSFSKAYVTGFTHHL 315
             ..|:.|:.::                    ||.|..|...:     .::||.:.|...  |:..
Yeast    57 YKGSIFHRVIKDFMCQFGDFTNFNGTGGESIYDEKFEDENFTVKHDKPFLLSMANAGPN--TNGS 119

  Fly   316 SFAISFKPLTVVNGSRVGFGRIVKGSKICECI--QSYGTKNGKLSRGLLFTSCGLL 369
            ...|:..|...::|..|.||.:::|.:|...|  |....:|.|..|.:....||:|
Yeast   120 QAFITCVPTPHLDGKHVVFGEVIQGKRIVRLIENQQCDQENNKPLRDVKIDDCGVL 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	44/184 (24%)
CPR6	NP_013317.1	cyclophilin_ABH_like	4..173	CDD:238907	41/181 (23%)
		TPR repeat	219..264	CDD:276809
		TPR repeat	269..303	CDD:276809
		TPR repeat	308..334	CDD:276809
		TPR_1	311..341	CDD:395414
		TPR repeat	342..368	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810