DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30350 and CPR4

DIOPT Version :9

Sequence 1:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_009995.1	Gene:	CPR4 / 850433	SGDID:	S000000665	Length:	318	Species:	Saccharomyces cerevisiae

Alignment Length:	205	Identity:	39/205 - (19%)
Similarity:	72/205 - (35%)	Gaps:	50/205 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 LPKSDAELRRLFRPR-----------IYFDLYLKDARPLGRFVVQLYTEAAPLVVLQL------I 247
            :...|.:|::.:.|.           .|||...|..:. .....:||....|..|...      :
Yeast    28 ITSKDVDLQKKYEPSPPATHRGIITIEYFDPVSKSMKE-ADLTFELYGTVVPKTVNNFAMLAHGV 91

  Fly   248 KSCM---------CNQHSKFMVKRLFPNLWLETDLMLSSDSLLHQPLE-YDAKVIDHGASSYVLS 302
            |:.:         ...:.|..:.:::||.:::..::.....    |.. |..|..|   .::.|.
Yeast    92 KAVIEGKDPNDIHTYSYRKTKINKVYPNKYIQGGVVAPDVG----PFTVYGPKFDD---ENFYLK 149

  Fly   303 FSK------AYVTGFTHHLSFAISFKP--LTVVNGSRVGFGRIVKG-SKICECIQ-----SYGTK 353
            ..:      ||....::...|.|:.|.  ...::|..|.||:|..| .::.:.||     .||..
Yeast   150 HDRPERLAMAYFGPDSNTSEFIITTKADGNEELDGKSVVFGQITSGLDQLMDAIQYTETDEYGKP 214

  Fly   354 NGKLSRGLLF 363
            ..:| |.|.|
Yeast   215 QHEL-RFLYF 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	37/193 (19%)
CPR4	NP_009995.1	cyclophilin	67..219	CDD:238194	29/159 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900