DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30350 and PPIAL4E

DIOPT Version :9

Sequence 1:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001137504.2	Gene:	PPIAL4E / 730262	HGNCID:	33997	Length:	164	Species:	Homo sapiens

Alignment Length:	162	Identity:	35/162 - (21%)
Similarity:	66/162 - (40%)	Gaps:	14/162 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 IYFDLYLKDARPLGRFVVQLYTEAAPLVVLQLIKSCMCNQHSKFMVK-----RLFPNLWLE---- 270
            ::|:: .:|.:||||..::|:.:..|......  ..:......|..|     |:.|....:
Human     6 VFFEI-TRDGKPLGRISIKLFADKIPKTAENF--RALSTGEKGFRYKGSCFHRIIPGFMCQGGDF 67

  Fly   271 TDLMLSSDSLLHQPLEYDAKVIDHGASSYVLSFSKAYVTGFTHHLSFAISFKPLTVVNGSRVGFG 335
            |....:.|..::.....|..:|.....|.:||.:.|...  |:...|.|.......::|..|.||
Human    68 TRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPN--TNGSQFFICAAKTEWLDGKHVAFG 130

  Fly   336 RIVKGSKICECIQSYGTKNGKLSRGLLFTSCG 367
            ::.:...|.|.::.:|.:|.|.|:.:....||
Human   131 KVKERVNIVEAMEHFGYRNSKTSKKITIADCG 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	35/162 (22%)
PPIAL4E	NP_001137504.2	cyclophilin	4..162	CDD:294131	33/160 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810