DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30350 and Ppil4

DIOPT Version :9

Sequence 1:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_080417.2	Gene:	Ppil4 / 67418	MGIID:	1914668	Length:	492	Species:	Mus musculus

Alignment Length:	143	Identity:	33/143 - (23%)
Similarity:	54/143 - (37%)	Gaps:	34/143 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 LGRFVVQLYTEAAPLVVLQLIKSCMCNQHSKFMVKRLFPNLWLETDLMLSS----------DSLL 281
            ||..|:.||||..|...|..:|.|....::..::..      ::.|.::.:          :|:.
Mouse     9 LGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHN------VQRDFIIQTGDPTGTGRGGESIF 67

  Fly   282 HQPLEYDA------KV--IDH---GASSYVLSFSKAYVTGFTHHLSFAISF-KPLTVVNGSRVGF 334
            .|.....|      ||  |.|   |..|.|.:.|.      .|...|.|:. :.|..::|....|
Mouse    68 GQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSD------QHGSQFLITTGENLDYLDGVHTVF 126

  Fly   335 GRIVKGSKICECI 347
            |.:.:|..|.:.|
Mouse   127 GEVTEGMDIVKKI 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	33/143 (23%)
Ppil4	NP_080417.2	cyclophilin_RRM	4..161	CDD:238902	33/143 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	167..188
		RRM	<193..>320	CDD:223796
		RRM_PPIL4	237..319	CDD:240681
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	368..409
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	423..492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900