DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30350 and Ppil2

DIOPT Version :9

Sequence 1:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_006522510.1	Gene:	Ppil2 / 66053	MGIID:	2447857	Length:	564	Species:	Mus musculus

Alignment Length:	312	Identity:	66/312 - (21%)
Similarity:	111/312 - (35%)	Gaps:	62/312 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 RIKGAISTVDA-EAPNFQAARITGVNNLRD--EAQTFMKR-----------TKANIQLLVEISRT 113
            |..|.:.|.:| |..|.:|      .||||  ..:.|.::           .|.|:.....:...
Mouse   120 RTTGNVYTYEAVEQLNIKA------KNLRDLLTDEPFSRQDIITLQDPTNLDKFNVSNFFHVKNN 178

  Fly   114 MRTHGAINPFRYDTVHAVSSIPMALL------TLEKLERDNRDF-GRRILEV------NSEVDSG 165
            ||   .|:|   |...|... |...|      |.|.|:...::| |..||..      ..:||.
Mouse   179 MR---IIDP---DEEKAKQD-PSYYLKNTNSETRETLQELYKEFKGDEILAATMRPPEKKKVDQ- 235

  Fly   166 LSDKRMREGRSSTPVAPLELPPQAMAKYEAFNIPLPKSDAELRR--LFRPRIYFDLYLKDARPLG 228
            |:......|:.|.......:.|:  ..:||..|     |.::.|  ..:.:.|..|:...    |
Mouse   236 LNAAHYSTGKVSASFTSTAMVPE--TTHEAAVI-----DEDVLRYQFVKKKGYVRLHTNK----G 289

  Fly   229 RFVVQLYTEAAPLVVLQLIKSCMCNQHSKFMVKRLFPNLWLE----TDLMLSSDSLLHQPLEYDA 289
            ...::|:.:..|......||.|....:...:..|...|..::    |......:|...:|.:.:.
Mouse   290 DLNLELHCDLTPKTCENFIKLCKKQYYDGTIFHRSIRNFVIQGGDPTGTGTGGESFWGKPFKDEF 354

  Fly   290 KV-IDHGASSYVLSFSKAYVTGFTHHLSFAISFKPLTVVNGSRVGFGRIVKG 340
            :. :.|.... |||.:.:...  |:...|.|:|:....::.....|||:|.|
Mouse   355 RPNLSHTGRG-VLSMANSGPN--TNKSQFFITFRSCAYLDKKHTIFGRVVGG 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590	27/112 (24%)
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	26/134 (19%)
Ppil2	XP_006522510.1	RING-Ubox_PPIL2	38..110	CDD:319577
		RING_Ubox	100..159	CDD:388418	12/44 (27%)
		U-box domain, a modified RING finger	103..146	CDD:319361	11/31 (35%)
		cyclophilin_RING	281..440	CDD:238904	26/130 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900