DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30350 and nrm

DIOPT Version :9

Sequence 1:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001246890.1	Gene:	nrm / 40515	FlyBaseID:	FBgn0262509	Length:	2192	Species:	Drosophila melanogaster

Alignment Length:	149	Identity:	27/149 - (18%)
Similarity:	57/149 - (38%)	Gaps:	35/149 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 DTVH----AVSSIPMALLTLEKLERDNRDFGRRILEVNSEVDSGLSDKRMREGRSSTPVAPLELP 186
            ||.|    ...::.:.:.:.||     .|.|....::::.:..|.||:::.......|...:.:.
  Fly   423 DTTHYKGGNSENVALVIKSTEK-----EDIGNYSCQLSNNIGKGTSDQKINLDVQYAPTVEILMI 482

  Fly   187 PQAMAKYEAFNIPLPKSDAELRRLFRPRIYFDLYLKDARPLGRFVVQLYTEAAPLVVLQLIKSC- 250
            |:.         |:.:||.....||       ..:.||.|.....|:.|..:   .:|:.:..|
  Fly   483 PEG---------PVKESDESNVTLF-------CNVLDANPSVLTKVRWYANS---TLLKELPDCE 528

  Fly   251 -----MCN-QHSKFMVKRL 263
                 :|: ..||.:::.:
  Fly   529 ETREDLCHIDPSKLLLESI 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590	7/32 (22%)
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	10/59 (17%)
nrm	NP_001246890.1	Ig	44..152	CDD:299845
		Ig	176..248	CDD:299845
		Ig	277..354	CDD:299845
		IG_like	383..463	CDD:214653	8/44 (18%)
		Ig	394..463	CDD:143165	8/44 (18%)
		Ig_3	585..652	CDD:290638
		Ig	685..>719	CDD:299845
		IG_like	788..869	CDD:214653
		Ig	<811..869	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3515
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900