DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30350 and Ppid

DIOPT Version :9

Sequence 1:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_001004279.1	Gene:	Ppid / 361967	RGDID:	1303174	Length:	370	Species:	Rattus norvegicus

Alignment Length:	181	Identity:	42/181 - (23%)
Similarity:	72/181 - (39%)	Gaps:	36/181 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 PRIYFDLYLKDARPLGRFVVQLYTEAAPLVVLQLIKSCM-----------------CNQH---SK 257
            ||::||:.:...| :||.|::|:.:..|.........|.                 |..|   .|
  Rat    16 PRVFFDVDIGGER-VGRIVLELFADIVPKTAENFRALCTGEKGTGPTTGKPLHFKGCPFHRIIKK 79

  Fly   258 FMVK-RLFPNLWLETDLMLSSDSLLHQPLEYDAKVIDHGASSYVLSFSKAYVTGFTHHLSFAISF 321
            ||:: ..|.|     ......:|:..:..|.:.....|.... :||.:.|...  |:...|.|:.
  Rat    80 FMIQGGDFSN-----QNGTGGESIYGEKFEDENFHYKHDREG-LLSMANAGPN--TNGSQFFITT 136

  Fly   322 KPLTVVNGSRVGFGRIVKG---SKICECIQSYGTKNGKLSRGLLFTSCGLL 369
            .|...::|..|.||:::||   :::.|.::..|.|..||   .:...||.|
  Rat   137 VPTPHLDGKHVVFGQVIKGLGVARMLENVEVNGEKPAKL---CVIAECGEL 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	41/179 (23%)
Ppid	NP_001004279.1	cyclophilin_ABH_like	16..182	CDD:238907	39/177 (22%)
		Chaperone activity. /evidence=ECO:0000250	185..215		42/181 (23%)
		3a0801s09	192..>330	CDD:273380
		Interaction with HSP90AB1. /evidence=ECO:0000250	214..370
		TPR repeat	223..251	CDD:276809
		TPR repeat	272..302	CDD:276809
		TPR repeat	307..335	CDD:276809
		TPR repeat	341..364	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810