DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30350 and cyn-4

DIOPT Version :9

Sequence 1:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_496337.1	Gene:	cyn-4 / 174674	WormBaseID:	WBGene00000880	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	216	Identity:	42/216 - (19%)
Similarity:	73/216 - (33%)	Gaps:	49/216 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 EVNSEVDSGLSDKRMREGRSSTPVAPLELPPQAMAKYEAFNIPLPKSDAELRRLFRPRIYFDLYL 221
            |:|:   :..|..::..|.:||.:||:.....|:...:.......|.:|.:|.:..
Worm   235 EINA---AHYSQGKVAAGFTSTVMAPVTSNKAAVLDNDTVRYSRVKKNAFVRLVTN--------- 287

  Fly   222 KDARPLGRFVVQLYTEAAPLVVLQLIKSCMCNQHSKFMVKRLFPNLWLETDLMLSSDSLLHQPLE 286
                 .|...::|:....|......|..|....::.....||..|..|:..
Worm   288 -----FGPLNLELFAPKVPKACENFITHCSNGYYNNTKFHRLIKNFMLQGG-------------- 333

  Fly   287 YDAKVIDHGASS-YVLSFSKAYVTGFTHHL----------------SFAISFKPLTVVNGSRVGF 334
             |.....||..| :...||..:::||:|..                .|.|:|:|...::.....|
Worm   334 -DPTGTGHGGESIWDKPFSDEFISGFSHDARGVLSMANKGSNTNGSQFFITFRPCKYLDRKHTIF 397

  Fly   335 GRIVKGSKICECIQSYGTKNG 355
            ||:|.|......|:...|:.|
Worm   398 GRLVGGQDTLTTIEKLETEEG 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	30/161 (19%)
cyn-4	NP_496337.1	Ubox	45..96	CDD:128780
cyn-4	NP_496337.1	cyclophilin_RING	281..440	CDD:238904	31/167 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900