DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30350 and Ppif

DIOPT Version :9

Sequence 1:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_598845.1	Gene:	Ppif / 105675	MGIID:	2145814	Length:	206	Species:	Mus musculus

Alignment Length:	175	Identity:	45/175 - (25%)
Similarity:	72/175 - (41%)	Gaps:	32/175 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 PRIYFDLYLKDARPLGRFVVQLYTEAAPLVVLQLIKSCMCNQHSKFMVK-----RLFPNLWLETD 272
            |.:|.|:. .|.:||||.|::|..:..|......  ..:|.....|..|     |:.|....:
Mouse    45 PLVYLDVG-ADGQPLGRVVLELKADVVPKTAENF--RALCTGEKGFGYKGSTFHRVIPAFMCQ-- 104

  Fly   273 LMLSSDSLLHQ------------PLE-YDAKVIDHGASSYVLSFSKAYVTGFTHHLSFAISFKPL 324
               :.|...|.            |.| :..|.:..|    |||.:.|...  |:...|.|.....
Mouse   105 ---AGDFTNHNGTGGRSIYGSRFPDENFTLKHVGPG----VLSMANAGPN--TNGSQFFICTIKT 160

  Fly   325 TVVNGSRVGFGRIVKGSKICECIQSYGTKNGKLSRGLLFTSCGLL 369
            ..::|..|.||.:.:|..:.:.|:|:|:|:||.|:.::.|.||.|
Mouse   161 DWLDGKHVVFGHVKEGMDVVKKIESFGSKSGKTSKKIVITDCGQL 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	44/173 (25%)
Ppif	NP_598845.1	cyclophilin_ABH_like	45..203	CDD:238907	42/171 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810