DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30345 and CG42514

DIOPT Version :9

Sequence 1:	NP_724760.2	Gene:	CG30345 / 246553	FlyBaseID:	FBgn0050345	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_730171.1	Gene:	CG42514 / 8674108	FlyBaseID:	FBgn0260388	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	124/516 - (24%)
Similarity:	223/516 - (43%)	Gaps:	65/516 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DDEEPIIGADDEPLDIEVRSPPPSNRTFSSWLKR-PRSLILEPAVFLVFFGRFLTDAVYQNQILY 67
            |:|....|...|..|      ..:.||...|... .:|..:||.:||..|...:|..|.||..||
  Fly    25 DNENSASGTVREQRD------EAAGRTVLQWAWHVVKSTSVEPTMFLYMFAFMITSVVEQNFFLY 83

  Fly    68 QTCVTVMKYNATECEPFLGTDRASDEVKKIEGQVQEYASTIT-----MISSMLESTVPAIVSLFL 127
            ::|.....:....|.          .:.|.|.:.....:.:|     ...::.....|.|::|||
  Fly    84 KSCRVNRNFTEEICR----------NLNKPENEEFRTKAMLTNAWFLQWENISAHVFPIILALFL 138

  Fly   128 GPWSDKFGRRPILLSTFTGYLFSAIILVVLTQITT--AVNISPWWFLLSSVPSVFSGGTCALITI 190
            |.:||:.||:..||....|..|.:.::||..::||  ..||    ...:::||..:|...|:...
  Fly   139 GSFSDRRGRKLPLLMGLVGKFFYSTMIVVNARMTTWPVQNI----IYSATLPSALTGADVAIFAS 199

  Fly   191 LYCYVSDVATENKRAMRMVTMEAALGLGMMAGGVASG--YIYAATGASI--LFILVGSIISIALL 251
            .:.|:||:::..:|.:| ||:...:.|..|..|||.|  ..|.....|.  :|.:..|::::|::
  Fly   200 CFAYISDISSLQQRTIR-VTILDVIYLSAMPMGVALGSHLFYNVFNQSYADMFTVNASLLALAII 263

  Fly   252 YVYFFVAESLKSEDLETGSRIRE---------FFRLDLVKVLVKTCIRKRENYDRAIIWFVMMSL 307
            |...    :||.:.......:||         ||....||..:...::.|:.:.|:.:..:::|:
  Fly   264 YTLC----ALKWQTTPRQRSLRELGCCGFWGDFFDKQHVKDSLAVLVKPRKGHRRSFLIILLVSM 324

  Fly   308 TLCVFAMEGESTVNYMFMRKQFDYTVQDYSVFNAARVVIQVVGSTIAMILLRRLLGLSTIMMTLL 372
            .|..|..: |....||:...:||:.|..||.|...:....|:...:|:.|:.::||...   |.:
  Fly   325 ALYTFQRD-EGQYLYMYTLGKFDWDVSAYSNFKTFKSSAYVIAMLLAVPLMNKILGWRD---TTI 385

  Fly   373 AFACCVLESTVRATAVYGSE---MYLALMVGMMRGVMSPMCKAILSHVTPSSELGKIFSLTTSLQ 434
            .|......|..|....:.:.   :|...:|..:..::.||.:|:.|.:.|:||.||:|:|.:...
  Fly   386 IFIGTWAHSIARLFFYFATNTDLLYAGAVVCSLGPIVGPMIRAMTSKIVPTSERGKVFALLSVCD 450

  Fly   435 SISPLGAAPLYTAVYQATVNFYPGIFNFI-----SVGLYFLCFCMSAAVFGIQKSMGSNSV 490
            :..|..:...|:.:|:.|.|...|...||     .:.::.:..|:...       :|.||:
  Fly   451 NAVPFISGVCYSQLYRRTQNTNHGGNVFILTIATQIAVFVMILCLHIV-------LGKNSL 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30345	NP_724760.2	MFS_1	102..437	CDD:284993	88/357 (25%)
CG30345	NP_724760.2	MFS	121..472	CDD:119392	94/373 (25%)
CG42514	NP_730171.1	MFS_1	129..458	CDD:284993	88/341 (26%)
CG42514	NP_730171.1	MFS	132..495	CDD:119392	94/375 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458937
Domainoid	1	1.000	70	1.000	Domainoid score	I9497
eggNOG	1	0.900	-	-		E1_KOG2816
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	1	1.000	-	-		mtm6480
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	P	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
	11	10.800