DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30345 and slc46a3

DIOPT Version :9

Sequence 1:	NP_724760.2	Gene:	CG30345 / 246553	FlyBaseID:	FBgn0050345	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_009303566.1	Gene:	slc46a3 / 556282	ZFINID:	ZDB-GENE-100105-2	Length:	475	Species:	Danio rerio

Alignment Length:	479	Identity:	104/479 - (21%)
Similarity:	206/479 - (43%)	Gaps:	65/479 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RSLILEPAVFLVFFGRFLTDAVYQNQILYQTCVTVMKYNATECEPFLGTDRASDEVKKIEG---- 99
            |..::||||.|..|..|:...:.| |.:|:..       ..|...|:.|..:.........
Zfish     3 RVSLIEPAVGLYAFAMFMFYPLLQ-QYVYRRL-------WFELSGFIYTSESLSHCSSNHSYITL 59

  Fly   100 -QVQEYASTITMISSMLESTVPAIVS-LFLGPWSDKFGRRPILLSTFTGYLFSAIILVVLTQITT 162
             |..:..:::.::.|.|...:|:::| |.|..:||..||:..::....|....|:..|::::.:.
Zfish    60 HQAVQKETSLFLLHSELCFLIPSLISALLLVSYSDYCGRKVAIVPPLVGEALHALSYVLVSRFSF 124

  Fly   163 AVNISPWWFLLSSVPSVFSGGTCALITILYCYVSDVA---TENKRAMRMVTMEAALGLGMMAGGV 224
            ::|    :.|.||..|...||...||...:.||:|:.   .|.::.:||..::..||:......:
Zfish   125 SLN----YLLASSFMSGLMGGPPTLIGGCFAYVADLCGEDLEGQKTVRMARLDMILGVLTGLASL 185

  Fly   225 ASGYIYAATGASILFILVGSIISIALLYVYFFVAESL---------KSEDLETGSRIRE----FF 276
            .:|:...|.|.:..|:....:..|.||||...:.|||         .|.......|:|:    ..
Zfish   186 CTGFFIKAAGFTWPFLTAVFLHLINLLYVLVVLKESLVLPNSAVSTSSPSASEAPRLRQTQALTT 250

  Fly   277 RLDLVKVLVKTCIRKRENYDRAIIWFVMMSLTLCVF-----AMEGESTVNYMFMRKQFDYTVQDY 336
            ||..|.:|.....|:|.         |::.|.|..|     |::|..::   |:..:.:..:...
Zfish   251 RLQGVYLLFAASNRRRN---------VVLLLMLAAFAFFKLALQGGWSI---FILYELNTPLCWS 303

  Fly   337 SVF----NAARVVIQVVGSTIAMILLRRLLGLSTIMMTLLAFACCVLESTVRATAVYGSEMYLAL 397
            .||    :|....|.:|......:|.|.|.....|::.|::.|..::.:....|.:....:.|.|
Zfish   304 EVFVGYGSALSTAIYLVSFAGVALLSRCLPDAYIILLGLMSVAAGLIMAAFAKTTLLMFLVRLPL 368

  Fly   398 MVGMMRGVMSPMCKAILSHVTPSSELGKIFSLTTSLQSISPLGAAPLYTAVYQATVNFYPGIFNF 462
            ::.:|   .:|:.::::|.:...||.|.:|:....::.:|...:..::.::|.||::::.|....
Zfish   369 LLSIM---PTPVLRSMMSKIVSGSEQGAMFACVAFVEMLSVGVSFTVFNSIYAATLSWFSGFSFL 430

  Fly   463 ISVGL-----YFLC--FCMSAAVF 479
            ::.||     ..:|  .|:...|:
Zfish   431 LAAGLTVIPSALICVILCLRLDVY 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30345	NP_724760.2	MFS_1	102..437	CDD:284993	79/360 (22%)
CG30345	NP_724760.2	MFS	121..472	CDD:119392	84/383 (22%)
slc46a3	XP_009303566.1	MFS_1	77..409	CDD:284993	78/350 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6513
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.830