DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30345 and CG15553

DIOPT Version :9

Sequence 1:	NP_724760.2	Gene:	CG30345 / 246553	FlyBaseID:	FBgn0050345	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_651841.3	Gene:	CG15553 / 43677	FlyBaseID:	FBgn0039817	Length:	521	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	150/497 - (30%)
Similarity:	269/497 - (54%)	Gaps:	49/497 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 WLKRPRSLILEPAVFLVFFGRFLTDAVYQNQILYQTCVTVMKYNATECEPFLGTDRASDEVKKIE 98
            |.:......:||.:|::.|...|:..|.:||::||.|..:.:||.|:|: .|.:...:.|::.||
  Fly    14 WGRLFNMFYIEPVLFMLIFSHMLSGTVMRNQLIYQACTVIFQYNETDCK-LLDSKNTTTEIQAIE 77

  Fly    99 GQVQEYASTITMISSMLESTVPAIVSLFLGPWSDKFGRRPILLSTFTGYLFSAIILVVLTQITTA 163
            .::|:|.:.:.:..::.||.:|||..||:|.|||::||:|:::.:..|:..||:|..::..:::.
  Fly    78 TELQDYVANMFLTRTLFESIMPAICGLFVGSWSDQYGRKPLMIVSLVGFSASALISSIICWLSSY 142

  Fly   164 VNISPWWFLLSSVPSVFSGGTCALITILYCYVSDVATENKRAMRMVTMEAALGLGMMAGGVASGY 228
            ..::|||:.|::||....||.|......:|:::|......|..||:.||..|.:.:.:|.:.|.:
  Fly   143 YMVNPWWYTLAAVPHSVLGGWCVFSVAAFCFITDTTDMKTRPYRMIFMEIILFVALTSGSLLSSF 207

  Fly   229 IYAATGASILFILVGSIISIALLYVYFFVAESL-------------------------------- 261
            :||||.::.:..|...|:.||.|::.|::.|||
  Fly   208 VYAATSSAFVQSLSCLIVIIATLFIIFYLPESLGMSPEEDEIPEKEKNVVVTVLDHKNKTNEISA 272

  Fly   262 ---KSED-------------LETGSRIREFFRLDLVKVLVKTCIRKRENYDRAIIWFVMMSLTLC 310
               |:|:             ||........|.:..||.:..||.:||||....|||.|.::..:.
  Fly   273 EAEKTENCDDPPKYESPEKPLEDKVEKAGLFSIKHVKDMFSTCFKKRENNAHTIIWLVTLAGFVS 337

  Fly   311 VFAMEGESTVNYMFMRKQFDYTVQDYSVFNAARVVIQVVGSTIAMILLRRLLGLSTIMMTLLAFA 375
            :|..:|..||||:|:|:||.:||:|:::|......:.::|:.:.:::||:..|||.:.:.||:..
  Fly   338 IFVADGVMTVNYLFVRQQFHFTVRDFTIFETFSQSVPMLGAVLGILILRKFFGLSVVALALLSLL 402

  Fly   376 CCVLESTVRATAVYGSEMYLALMVGMMRGVMSPMCKAILSHVTPSSELGKIFSLTTSLQSISPLG 440
            ..|..:..|..|.....:||::::|:.|.:..||.:.|:|::.|.|:.||:|::...|||.:|..
  Fly   403 SEVAANIARGFAYLSWHLYLSVVLGIFRSIQGPMFRTIVSNIVPPSDTGKLFAIGNILQSFAPFV 467

  Fly   441 AAPLYTAVYQATVNFYPGIFNFISVGLYFLCFCMSAAVFGIQ 482
            |||||||:|:.::...||.|||:|...|.|.|.:...|..|:
  Fly   468 AAPLYTAIYKESLASNPGGFNFLSAAFYGLAFILIGWVMRIK 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30345	NP_724760.2	MFS_1	102..437	CDD:284993	110/382 (29%)
CG30345	NP_724760.2	MFS	121..472	CDD:119392	122/398 (31%)
CG15553	NP_651841.3	MFS_1	96..469	CDD:284993	108/372 (29%)
CG15553	NP_651841.3	MFS	97..239	CDD:304372	45/141 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458930
Domainoid	1	1.000	92	1.000	Domainoid score	I7560
eggNOG	1	0.900	-	-		E1_KOG2816
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4421
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	1	1.000	-	-		mtm6480
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
	10	9.900