DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30345 and slc46a1

DIOPT Version :9

Sequence 1:	NP_724760.2	Gene:	CG30345 / 246553	FlyBaseID:	FBgn0050345	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_956579.1	Gene:	slc46a1 / 393255	ZFINID:	ZDB-GENE-040426-1012	Length:	481	Species:	Danio rerio

Alignment Length:	504	Identity:	121/504 - (24%)
Similarity:	198/504 - (39%)	Gaps:	98/504 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPRDDEEPIIGADDEPLD----------IEVRSPPPSNRTFSSWLKRPRSLILEPAVFLVFFGRF 55
            |...|...|:..|.|.:|          .|.::|||.:        .|.|:.:||.:||..|. .
Zfish     1 MEDSDTSAILAEDSESVDSRTVCRCFRVTENKAPPPCS--------CPLSVTVEPVMFLSTFS-I 56

  Fly    56 LTDAVYQNQILYQTCVTVMKYNATECEPFLGTDRASDEVKKIEGQVQEYASTITMISSMLESTVP 120
            :..|....|.|:......:.||        ||.........:...:|....|:|...|:..:...
Zfish    57 VLQAPLCTQYLWDRLSEDVGYN--------GTKTGGCNASTVHDPLQTEVETLTAHWSLYINLGG 113

  Fly   121 AIVSLF----LGPWSDKFGRRPILLSTFTGYLFSAIILVVLTQITTAVNISPWWFLLSSVPSVFS 181
            .:|.||    ||.|||:.|||.:|:....|....|.:.:.:..:...|    :|||:..:.|..|
Zfish   114 FLVGLFMVILLGSWSDRAGRRLVLIIPSLGLAVQAAVYLTVMYLKLPV----FWFLIGRICSGLS 174

  Fly   182 GGTCALITILYCYVSDVATENKRAMRMVTMEAALGLGMMAGGVASGYIYAATGASILFILVGSII 246
            |...|::...:.||:|.:....|..|:..:||.|||..|...:..|....|.|....|.||.:..
Zfish   175 GDFNAILAGCFAYVADTSERGSRTFRVAILEACLGLAGMFASIIGGQWRRAQGYINPFWLVLATN 239

  Fly   247 SIALLYVYFFVAES--------------------LKSEDLETGSR------IREFFRLDLVKVLV 285
            ..|.||.|.||.|:                    |.|.|...|.|      |..||   ||..:.
Zfish   240 LTAALYAYLFVPETVTPDPQARLFSTRHHQAVCRLYSSDAPPGRRSKLWLYILCFF---LVVTVH 301

  Fly   286 KTCIRKRENYDRAIIWFVMMSLTLCVFAMEGESTVNYMFMRKQFDYTVQDYSVFNAARVVIQVVG 350
            ..|......|:        :|..||    .|...:.|....|...| :...:...|.:..::  .
Zfish   302 LGCSDLYVLYE--------LSAPLC----WGPELIGYGSAAKHLAY-LTSLTGLRAMQCCLE--D 351

  Fly   351 STIAMILLRRLLGLSTIMMTLLAFACCVLESTVRATAVYG-SEMYLALMVGMMRGVMSPMCKAIL 414
            |.:|      |:||::.|:.|:..:  |.::|......|| ..:::|         .:|:.::.|
Zfish   352 SWVA------LVGLTSNMVGLVVIS--VADTTALMFTGYGLCFLFMA---------STPVLRSKL 399

  Fly   415 SHVTPSSELGKIFSLTTSLQSISPLGAAPLYTAVYQATVNFYPGIFNFI 463
            |.:...:|.|.:|:....::.:..|.::.::.|:|.||::|..| |.|:
Zfish   400 SKLVDPAEQGALFASVACVEGLCSLVSSGVFNALYPATLHFMKG-FPFV 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30345	NP_724760.2	MFS_1	102..437	CDD:284993	88/365 (24%)
CG30345	NP_724760.2	MFS	121..472	CDD:119392	93/374 (25%)
slc46a1	NP_956579.1	MFS	93..460	CDD:119392	97/395 (25%)
slc46a1	NP_956579.1	MFS_1	114..427	CDD:284993	85/351 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6480
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.830