DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30345 and CG30344

DIOPT Version :9

Sequence 1:	NP_724760.2	Gene:	CG30345 / 246553	FlyBaseID:	FBgn0050345	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_724759.1	Gene:	CG30344 / 246552	FlyBaseID:	FBgn0050344	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	513	Identity:	313/513 - (61%)
Similarity:	397/513 - (77%)	Gaps:	23/513 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPRDDEEPII-----GADDEPLDIEVRS------------PPPSNRTFSSWLKRPRSLILEPAVF 48
            |||.|.|.::     |.|..|..::..|            |||.:  :||:    |..|||||||
  Fly     1 MPRSDTEALVADVETGEDSAPRILDASSAASSEQVDPPPVPPPHD--YSSY----RWFILEPAVF 59

  Fly    49 LVFFGRFLTDAVYQNQILYQTCVTVMKYNATECEPFLGTDRASDEVKKIEGQVQEYASTITMISS 113
            |:||.|.|..||||||||||||:|:.|:|||:|||.||.||.||..|::|..||.|::.|.|.:|
  Fly    60 LIFFARNLIGAVYQNQILYQTCITIEKFNATQCEPLLGIDRGSDADKEVEVIVQTYSANIMMTTS 124

  Fly   114 MLESTVPAIVSLFLGPWSDKFGRRPILLSTFTGYLFSAIILVVLTQITTAVNISPWWFLLSSVPS 178
            :|||.:||..||||||||||||||||||:||||||..|:||:|:|.||.:.||||||||||||||
  Fly   125 LLESIIPAFASLFLGPWSDKFGRRPILLTTFTGYLTGALILIVITYITRSTNISPWWFLLSSVPS 189

  Fly   179 VFSGGTCALITILYCYVSDVATENKRAMRMVTMEAALGLGMMAGGVASGYIYAATGASILFILVG 243
            |.|||||||||.:|||:||||.|.|:|:|||..||:|..|:|.|.||||||||||.|.:||.:.|
  Fly   190 VVSGGTCALITGIYCYISDVAKERKKALRMVLNEASLCAGIMVGNVASGYIYAATNALVLFSIAG 254

  Fly   244 SIISIALLYVYFFVAESLKSEDLETGSRIREFFRLDLVKVLVKTCIRKRENYDRAIIWFVMMSLT 308
            |::..||:||..||.|||...|:.||||:|||||.|||..|::||.::|.|:||.|||..|::||
  Fly   255 SLMMFALMYVLLFVPESLNPGDIHTGSRVREFFRFDLVTDLIRTCFKRRPNFDRTIIWLTMIALT 319

  Fly   309 LCVFAMEGESTVNYMFMRKQFDYTVQDYSVFNAARVVIQVVGSTIAMILLRRLLGLSTIMMTLLA 373
            :.:|.|||||||||||::.:|::|::|:|:|||:|:|||:|||.:.|::|||:|.:|.:.|.:|:
  Fly   320 IAIFDMEGESTVNYMFVQDKFNWTIKDFSLFNASRIVIQIVGSIVGMLVLRRVLKMSIVTMAMLS 384

  Fly   374 FACCVLESTVRATAVYGSEMYLALMVGMMRGVMSPMCKAILSHVTPSSELGKIFSLTTSLQSISP 438
            .|||||||||||||||..|:||.:.:|||||||.|||:||||||.|::|:||||:||||::|:||
  Fly   385 LACCVLESTVRATAVYWQELYLGMTLGMMRGVMGPMCRAILSHVAPATEVGKIFALTTSMESVSP 449

  Fly   439 LGAAPLYTAVYQATVNFYPGIFNFISVGLYFLCFCMSAAVFGIQKSMGSNSVYQAIGS 496
            ||||||||.||:||:..|||.|||||..|||:|:.:.|.:|||||||||:||||||||
  Fly   450 LGAAPLYTTVYKATLENYPGAFNFISAALYFVCYILIAVIFGIQKSMGSSSVYQAIGS 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30345	NP_724760.2	MFS_1	102..437	CDD:284993	213/334 (64%)
CG30345	NP_724760.2	MFS	121..472	CDD:119392	229/350 (65%)
CG30344	NP_724759.1	MFS	113..490	CDD:119392	240/376 (64%)
CG30344	NP_724759.1	MFS_1	128..448	CDD:284993	206/319 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458925
Domainoid	1	1.000	92	1.000	Domainoid score	I7560
eggNOG	1	0.900	-	-		E1_KOG2816
Homologene	1	1.000	-	-		H124683
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4421
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	1	1.000	-	-		mtm6480
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	P	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
	12	11.800