DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30345 and slc-46A

DIOPT Version :9

Sequence 1:	NP_724760.2	Gene:	CG30345 / 246553	FlyBaseID:	FBgn0050345	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_500781.2	Gene:	slc-46A / 189356	WormBaseID:	WBGene00021159	Length:	469	Species:	Caenorhabditis elegans

Alignment Length:	458	Identity:	116/458 - (25%)
Similarity:	194/458 - (42%)	Gaps:	74/458 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RSLILEPAVFLVFFGRFLTDAVYQNQILYQTCVTVMKYNATECEPFLGTDRASDEVKKIEGQVQE 103
            |.|.:|..:||...|.:|...|:||.|..:.|:...:.|.|.|..........|        :|.
Worm     6 RMLGMEIPLFLYMLGSYLNYPVFQNLIYEKECLIKYQQNETFCRNVSAYYDDKD--------IQA 62

  Fly   104 YASTITMISSMLESTVPAIVSLFLGPWSDKFGRRPILLSTFTGYLFSAIILVVLTQITTAVNISP 168
            .|:....|||:.......:.:|.||..:|.:..:..|:..:.|.:...|..|..:..   ::.|.
Worm    63 AANHFYFISSLTLLCPSLVTTLLLGAATDYWSIKIPLIIPYIGCILGTINYVFQSYF---IHTSV 124

  Fly   169 WWFLLSSVPSVFSGGTCALITILYCYVSDVATENKRAMRMVTMEAALGLGMMAGGVASGYIYAAT 233
            ::.|:|.......||..|:|:....|....:....|:.|:..:|.|:|||...|...||.|..|.
Worm   125 YFLLISDALFGLCGGFIAIISTTLTYGVKTSMLRYRSYRIAGVEGAIGLGGTVGFALSGTIREAC 189

  Fly   234 GASILFILVGSIISIALLYVYFFVAESLKSEDLE----------TGSR----IREFFRLDLVKVL 284
            |.::.|:::..:..:||||: ..:|:..|.|.:.          ||.:    ||||:|:
Worm   190 GYAVTFLIILGLQLLALLYL-LGLAKETKFEPVRPDEHTSLISTTGKQLVAVIREFYRV------ 247

  Fly   285 VKTCIRKRENYDRAIIWFVMMSLTLCVFAME-----GESTVNYMFMRKQFDYTVQDYSVFNAARV 344
                |.|...:.      :::.|.|..|.:|     |.|.:.|.::|.:..:..:.|..|:....
Worm   248 ----ITKSRQFR------LLLILNLLAFGLEMLVFSGLSDIQYSYLRYKLQWGDKKYGWFSGLSY 302

  Fly   345 VIQVVGSTIAMILLRRL-------------LGLSTIMMTLLAFACCVLESTVRATAVYGSEMYLA 396
            .|    :|.|::.|..|             |||...|::|..||  .|::.|.|        |..
Worm   303 GI----TTAAVLFLYPLLRMKLMSDGMLATLGLFFKMISLFMFA--FLQNEVMA--------YSI 353

  Fly   397 LMVGMMRGVMSPMCKAILSHVTPSSELGKIFSLTTSLQSISPLGAAPLYTAVYQATVNFYPGIFN 461
            .::.|....:|...:|.:|.:....|.|||||:.:.|:.|:.|.|..:|..||..|:.|:||:..
Worm   354 AVIVMFNRFVSTGFRAFISSLIDMQEQGKIFSVISLLEGITTLVATSIYNNVYPNTLTFFPGLLY 418

  Fly   462 FIS 464
            .||
Worm   419 LIS 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30345	NP_724760.2	MFS_1	102..437	CDD:284993	88/366 (24%)
CG30345	NP_724760.2	MFS	121..472	CDD:119392	95/376 (25%)
slc-46A	NP_500781.2	MFS_SLC46	7..436	CDD:340944	115/457 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3339
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14635
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.880