DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30345 and slcr-46.3

DIOPT Version :9

Sequence 1:	NP_724760.2	Gene:	CG30345 / 246553	FlyBaseID:	FBgn0050345	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_505506.2	Gene:	slcr-46.3 / 185544	WormBaseID:	WBGene00009582	Length:	585	Species:	Caenorhabditis elegans

Alignment Length:	554	Identity:	122/554 - (22%)
Similarity:	212/554 - (38%)	Gaps:	135/554 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LDIEVRSPPPS----------NRTFSSWLKRPRSLI---------------LEPAVFLVFFG--- 53
            |:.|...||.|          .|.||   .|.||..               :||.:|||..|
Worm    14 LESENAEPPQSEISMSVVTDDTRLFS---VRRRSTFHALNETKGVWCCPVNVEPILFLVMCGFGL 75

  Fly    54 ---------------------RFLTD-AVYQNQILYQTCVTVMKYNATECEPFLGTDRASDEVKK 96
                                 |.|.| |.|       ||.::...|.|          ..|:|:|
Worm    76 MTTNNSLFTYWARCVQIAQTHRELADNATY-------TCASIASSNGT----------LQDDVEK 123

  Fly    97 IEGQVQEYASTITMISSMLESTVPA-IVSLFLGPWSDKFGRR-PILLSTFTGYLFSAIILVVLTQ 159
                  :.|:|...:..|  .|:|. |||..:|.|||:.||: |:|.|.| |...:..||:..|.
Worm   124 ------DIANTKIYLQIM--GTIPTLIVSPLIGNWSDRNGRKSPLLFSLF-GLFINNFILLCATL 179

  Fly   160 ITTAVNISPWWFLLSSVPSVFSGGTCALITILYCYVSDVATENKRAMRMVTMEAALGLGMMAGGV 224
            ....||:..|:|:...:..:|.||.....|.|.....|...:.|.....|.....|...:.:.|:
Worm   180 TYETVNVYYWFFISEFMLGMFGGGAATFSTSLAIVTDDCRHKLKPGSSTVPFRVGLASFVQSIGM 244

  Fly   225 ASGYIYAATGASILFILVGSIIS--------------------IALLYVYFFVAES--LKSEDLE 267
            .:|.:.      :..:.|.:|||                    |:|:|..|||.|:  .|.||.
Worm   245 LNGTLI------VSLLAVPAIISVERHALSYVECAFIQTALSLISLIYAIFFVRETHFPKKEDF- 302

  Fly   268 TGSRIREFFRLDLVKVLVKTC-IRKRENYDRAIIWFVMM------SLTLCV--------FAMEGE 317
            :.:::.|...::..::..|.. :|:..:|...:...:.:      .|.|||        |.....
Worm   303 SYNQLNEAEEVEAEELPPKIIGMRRFTSYLENVFGVLTVRRPGWTRLCLCVSLAFVFIEFLSFDP 367

  Fly   318 STVNYMFMRKQFDYTVQDYSVFNAARVVIQVVGSTIAMILL--RRLLGLSTIMMTLLAFACCVLE 380
            :.:..:..|..|.:..:.:|.|:..|.::...|..:..|||  ...||..:::: :.|.||....
Worm   368 ALLLLLVKRLPFAWNDKLFSYFSLTRQLVNCFGMILCPILLTFSHWLGKDSLLI-IAALACSAAT 431

  Fly   381 STVRATAVYGSEMYLALMVGMMRGVMSPMCKAILSHVTPSSELGKIFSLTTSLQSISPLGAAPLY 445
            |.:.|.|.....::...:.|::.|.|.|..::.|..:....|..::.::.:.:.|.||:.::.::
Worm   432 SFLTAFATRTEHIFYTCIFGIVMGGMQPAYRSFLPRMVAKEETARLLTVVSIIISFSPILSSLIF 496

  Fly   446 TAVYQATVNFYPGIFNFISVGLYFLCFCMSAAVF 479
            ..::..|:.::||.       .:|:..|....||
Worm   497 NNIFNMTLTWWPGF-------AFFVSGCFQITVF 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30345	NP_724760.2	MFS_1	102..437	CDD:284993	84/375 (22%)
CG30345	NP_724760.2	MFS	121..472	CDD:119392	85/391 (22%)
slcr-46.3	NP_505506.2	MFS_SLC46	59..530	CDD:340944	111/506 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163340
Domainoid	1	1.000	75	1.000	Domainoid score	I5901
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I3339
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	1	1.000	-	-		otm14610
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.860