DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30345 and slc46a3

DIOPT Version :9

Sequence 1:	NP_724760.2	Gene:	CG30345 / 246553	FlyBaseID:	FBgn0050345	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_002934077.1	Gene:	slc46a3 / 100492828	XenbaseID:	XB-GENE-984436	Length:	473	Species:	Xenopus tropicalis

Alignment Length:	479	Identity:	111/479 - (23%)
Similarity:	212/479 - (44%)	Gaps:	57/479 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KRPRSL-ILEPAVFLVFFGRFLTDAVYQNQILYQTCVT------VMKYNATECEPFLGTDRASDE 93
            |.|:.. ::||.|.:..|..|.|..:.|..:..:..:.      :...|.:.||. ..:|.|...
Frog    12 KTPKMFRLVEPVVAIYCFASFFTFPLIQQYVYSRMLIEGSSDGFINGNNISHCET-NQSDPAYIH 75

  Fly    94 VKKIEGQVQEYASTITMISSMLESTVPAIV-SLFLGPWSDKFGRRPILLSTFTGYLFSAIILVVL 157
            .|:::.:...::||:.     |.:.:|::| :|.|..:.|:.||:..:|....|.|.|.:|...:
Frog    76 QKEVQKRASLFSSTLD-----LSALIPSLVMALILVSYGDRHGRKASILLPCLGALLSVLIYCAI 135

  Fly   158 TQITTAVNISPWWFLLSSVPSVFSGGTCALITILYCYVSDVATE-NKRAMRMVTMEAALGLGMMA 221
            ...|..:.:    ..||.|.|.|.||....|...:.||:|::.: .|:.:|:..::..||:....
Frog   136 AFFTLPLAV----LYLSYVISGFMGGFATFIGGCFSYVADLSKDAQKKNIRIAFVDMVLGVSSGL 196

  Fly   222 GGVASGYIYAATGASILFILVGSIISIALLYVYFFVAESLKSEDLETGSRIREFFRLDLVKVLVK 286
            .|:||||.....|.:..|::.|.:..|.:.|:.||:.|:::..:.:.....:|.|......|.:
Frog   197 AGIASGYFIRELGFNWSFLIPGLLHIINICYICFFLEETVQRSEFQQPVLSKEGFTELFTGVFL- 260

  Fly   287 TCIRKRENYDRAIIWFVMMSLTLCVFAMEGESTVNYMFMRKQFDYTVQDYSV---FNAARVVIQV 348
             ..|......|.::..::::..|.:.|..|..:   :|...:.|..:...||   :.:|......
Frog   261 -LFRNASCKKRVVLTLLLLAFMLYLLANFGAVS---LFTLYELDAPLCWDSVLVGWGSAFSTFCF 321

  Fly   349 VGSTIAMILLRRLL--------GLSTIM--MTLLAFACCVLESTVRATAVYGSEMYLALMVGMMR 403
            |||...:.|..|.|        |:::.:  :.|:||:...:            .|.|..:..:..
Frog   322 VGSFFGVYLFSRCLKDAYIVFIGMTSWIGGIILVAFSTTTI------------AMMLVRIPLLFA 374

  Fly   404 GVMSPMCKAILSHVTPSSELGKIFSLTTSLQSISPLGAAPLYTAVYQATVNFYPGIFNFISVGLY 468
            .:..|:.::|:|.|...:|.|.:|:....|:||:.:....:::|||.|||.::||....:|.|:.
Frog   375 AMPLPVLRSIMSKVVLENEQGALFACIACLESITGVLTITIFSAVYAATVMWFPGFSFLLSAGIC 439

  Fly   469 FLCFCMSAAVFGIQKSMGSNSVYQ 492
            .|.|    .:.||...:|    ||
Frog   440 LLPF----GIIGILLLIG----YQ 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30345	NP_724760.2	MFS_1	102..437	CDD:284993	78/349 (22%)
CG30345	NP_724760.2	MFS	121..472	CDD:119392	86/365 (24%)
slc46a3	XP_002934077.1	MFS_SLC46A3	17..443	CDD:341006	103/452 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	97	1.000	Domainoid score	I7096
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47543
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.030