DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30345 and slc46a2

DIOPT Version :9

Sequence 1:	NP_724760.2	Gene:	CG30345 / 246553	FlyBaseID:	FBgn0050345	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_031762441.1	Gene:	slc46a2 / 100487507	XenbaseID:	XB-GENE-988711	Length:	444	Species:	Xenopus tropicalis

Alignment Length:	457	Identity:	95/457 - (20%)
Similarity:	183/457 - (40%)	Gaps:	69/457 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LEPAVFLVFFGRFLTDAVYQNQILYQTCVTVMKYNATECEPFLGTDRASDEVKKIEGQVQEYAST 107
            :||.|    .|..:..:.|...:|   .|....||.:.    |.::..||:      :.|...|.
Frog     6 IEPVV----AGAQIASSFYDTGLL---LVVKSHYNQSS----LSSNSTSDD------EEQNAISN 53

  Fly   108 ITMISSMLESTVPAIVSLFLGPWSDKFGRRPILLSTFTGYLFSAIILVVLTQITTAVNISPWWFL 172
            ..:|.:::.:..|.:.:..|....||..|:..:.....||..|.:.|:.:....        |.:
Frog    54 FYLIHNLILALTPILSAYILANIGDKKSRKVPICVPLLGYFVSRMFLLFVILFN--------WPI 110

  Fly   173 LSSVPSVFSGGTCALITILYCYVSDVA----TENKRAMRMVTMEAALGLGMMAGGVASGYIY--- 230
            .....|....|.....|..:..|..||    :|:||::|::.:|...|:....|.:.||:|:
Frog   111 EVMFGSAALNGLTGFFTTYWAGVLAVASLGSSESKRSVRIIIIELVYGVAGFVGSLVSGHIFKNF 175

  Fly   231 --AATGASILFILVGSIISIALLY-VYFFVAESLK------SEDLETGSRIREFFRLDLVKVLVK 286
              |....|:|.||.....:.:|:| ::.|....::      :|..||.:.        |:|...:
Frog   176 DIANQKGSVLVILSLCFYAFSLIYSLFIFKIPRIEETGPGNTESTETSTL--------LMKNPTE 232

  Fly   287 TCIRK---RENYDRAIIWFVMMSLTLCVFAMEGESTVNYMFMRKQ-FDYTVQDYSVFNAARVVIQ 347
            |....   ..:..:..:..:.:|..|...|:.|...|...|:.|: ..:...:....|||..:|.
Frog   233 TSTANGVTMTSSSKVFLVLLFLSAILYNAAVGGAVDVLPFFIIKEPLSWGAVEVGYANAAGYLIF 297

  Fly   348 VVGSTIAMILLRRLLGLSTIMMTLLAFACCV-LESTVRATAVYGSEMYLALMVGMMRGVMSPMCK 411
            |..........:||.....|.:.:|:|:..: :...|:.|.::    |:|.:|.|...:..|..:
Frog   298 VTSFLGVYFFSKRLTDFVMIGIGILSFSAGIFIMGFVQWTFLF----YVARVVMMFSLIPLPTIR 358

  Fly   412 AILSHVTPSSELGKIFSLTTSLQSISPLGAAPLYTAVYQATVNFYPGIFNFISVGLYFLCFCMSA 476
            :::|.....|..||:|.:...|.||:.:.....:|.:|||::.::.|           |||.:::
Frog   359 SVISKHVQGSSYGKVFVVLQLLLSITHVVTLISFTKLYQASLKWFHG-----------LCFILAS 412

  Fly   477 AV 478
            .:
Frog   413 II 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30345	NP_724760.2	MFS_1	102..437	CDD:284993	74/355 (21%)
CG30345	NP_724760.2	MFS	121..472	CDD:119392	77/371 (21%)
slc46a2	XP_031762441.1	MFS	3..426	CDD:421695	95/457 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47543
Panther	1	1.100	-	-	O	PTHR23507
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110