Protein Alignment CG30344 and SLC46A2

DIOPT Version :10

• Sequence 1: NP_724759.1
• Gene: CG30344 / 246552
• FlyBaseID: FBgn0050344
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_149040.3
• Gene: SLC46A2 / 57864
• HGNCID: 16055
• Length: 475
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 89/432 - (20%)
• Similarity: 186/432 - (43%)
• Gaps: 77/432 - (17%)

  Fly   100 RGSDADKEVEVIVQTYSANIMMTTSLLESIIPAFASLFLGPWSDKFGRRPILLTTFTGYLTGALI 164
            ||:..|::...|     :|..:..:|:..:.|..::..||..||::.|:..:..:..|:|...|.
Human    63 RGALEDQQQRAI-----SNFYIIYNLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSRLG 122

  Fly   165 LIV---------ITYITRSTNISPWWFLLSSVPSVVSGGTCALITGIYCYISDVAKERKKALRMV 220
            |::         :.|...:.|             .:.||..|..:|:....|..:.|.::::|::
Human   123 LLLKVLLDWPVEVLYGAAALN-------------GLFGGFSAFWSGVMALGSLGSSEGRRSVRLI 174

  Fly   221 LNEASLCAGIMVGNVASGYIYA-----ATNALVLFSIAGSLMMFALMYVLLF--VPESL-NPGDI 277
            |.:..|......|::|||:::.     :...|:|.:.:.|...|||:|.||.  ||||: .|.
Human   175 LIDLMLGLAGFCGSMASGHLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPS-- 237

  Fly   278 HTGSRVREFFRFDLVTDLIRTC--------------------FKRRPNFDRTIIWLTMIALTIAI 322
                  :|....|.|:..:.|.                    .|.:|:  :|.|.|..:.  ..|
Human   238 ------QELPAVDTVSGTVGTYRTLDPDQLDQQYAVGHPPSPGKAKPH--KTTIALLFVG--AII 292

  Fly   323 FDMEGESTVNY--MFV-QDKFNWTIKDFSLFNASRIVIQIVGSIVGMLVLRRVLK-MSIVTMAML 383
            :|:....||:.  :|| ::...|.........|:...| .:.|.:|:||..|..: .:::.:.|:
Human   293 YDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAGYTI-FITSFLGVLVFSRCFRDTTMIMIGMV 356

  Fly   384 SLAC-CVLESTVRATAVYWQELYLGMTLGMMRGVMGPMCRAILSHVAPATEVGKIFALTTSMESV 447
            |... .:|.:.|:.|.::    |:...:.:...:.....|:.:|.:...:..||:|.:.....::
Human   357 SFGSGALLLAFVKETYMF----YIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLAL 417

  Fly   448 SPLGAAPLYTTVYKATLENYPGAFNFISAALYFVCYILIAVI 489
            :.:..:.||..:|:.|::.:.|:...:|:.|.|:..|.|:::
Human   418 TGVVTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIV 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30344	NP_724759.1	MFS_SLC46	51..490	CDD:340944	89/432 (21%)
SLC46A2	NP_149040.3	MFS_SLC46A2_TSCOT	19..460	CDD:341008	89/432 (21%)