DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30344 and si:dkey-5g14.1

DIOPT Version :9

Sequence 1:	NP_724759.1	Gene:	CG30344 / 246552	FlyBaseID:	FBgn0050344	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_009303600.1	Gene:	si:dkey-5g14.1 / 556497	ZFINID:	ZDB-GENE-091204-361	Length:	463	Species:	Danio rerio

Alignment Length:	458	Identity:	95/458 - (20%)
Similarity:	200/458 - (43%)	Gaps:	44/458 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 RWFILEPAVFLIFFARNLIGAVYQNQILYQTC---ITIEKF----NATQCEPLLGIDRGSDADKE 107
            |.:.:||.|.:..||..::..:.| |.:|:..   ||...:    |.:||    ..:..:...::
Zfish     3 RLYFIEPVVAIYAFASFMLYPLIQ-QYVYRRLWLEITNSTYPVSENTSQC----AANSSNHTSRQ 62

  Fly   108 VEVIVQTYSANIMMTTSLLESIIPA-FASLFLGPWSDKFGRRPILLTTFTGYLTGALILIVITYI 171
            .|  ||..::...|.|. |.|:||: ..:|.|..:||:.||:..::....|.|...|..:.:::.
Zfish    63 EE--VQKAASLFSMYTD-LSSMIPSLIVTLLLVSYSDQRGRKITIIMPLIGTLIYTLSFLTVSFF 124

  Fly   172 TRSTNISPWWFLLSSVPSVVSGGTCALITGIYCYISDVAKE-RKKALRMVLNEASLCAGIMVG-- 233
                .::.:..:::|..|.:.||...::.|.:.|::|:.:: ::|.|||.:  ..:..|::.|
Zfish   125 ----QLNLYLLIVASFVSALFGGIGTMLGGCFSYVADLCEDGKQKTLRMAV--VDMMIGMLAGVA 183

  Fly   234 NVASGYIYAATNALVLFSIAGSLMMFALMYVLLFVPESLNPGDIHTGSRVREFFRFDLVTDLIRT 298
            ::::||...|......|..:....:..|:|.:..:.|:      ....|.........:.:|..:
Zfish   184 SISTGYFLHAAGFNWPFFTSAIFQVVNLLYAIFILEET------RVIDRSETLACCQALRNLACS 242

  Fly   299 CFKRRPNFDRTIIWLTMIAL----TIAIFDMEGESTVNYMFVQDKFNWT---IKDFSLFNASRIV 356
            .:.......|...|:.::.:    :::..:..|.|......:.:...||   :...|..:.|..:
Zfish   243 IYSLFAGGSRRRTWVLVLLIITFSSLSFVNTGGLSIFTLYELNEPLCWTEILVGYGSAASTSIFI 307

  Fly   357 IQIVGSIVGMLVLRRVLKMSIVTMAMLSLACCVLESTVRATAVYWQELYLGMTLGMMRGVMGPMC 421
            ...||..:..|.|..:   :|..:.|||:|..:|.:....|.:   .::|.....|...:..|:.
Zfish   308 TSFVGVFLFSLCLPNI---AIAFIGMLSVAVSMLMTGFAKTTL---TMFLVRIPAMFAIMPFPVL 366

  Fly   422 RAILSHVAPATEVGKIFALTTSMESVSPLGAAPLYTTVYKATLENYPGAFNFISAALYFVCYILI 486
            |:::|.|...:|.|.:||.....|::|..|:|..::.:|.||:...||....:.|.|..:...|:
Zfish   367 RSMMSKVVSKSEQGALFACVAFTETLSTNGSAASFSRIYAATVAWCPGFVFLLGAGLCLIPMSLL 431

  Fly   487 AVI 489
            .::
Zfish   432 GIL 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30344	NP_724759.1	MFS	113..490	CDD:119392	79/388 (20%)
CG30344	NP_724759.1	MFS_1	128..448	CDD:284993	64/330 (19%)
si:dkey-5g14.1	XP_009303600.1	MFS	79..435	CDD:119392	75/374 (20%)
si:dkey-5g14.1	XP_009303600.1	MFS_1	81..393	CDD:284993	63/329 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6513
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.830