DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30344 and slc46a3

DIOPT Version :9

Sequence 1:	NP_724759.1	Gene:	CG30344 / 246552	FlyBaseID:	FBgn0050344	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_009303566.1	Gene:	slc46a3 / 556282	ZFINID:	ZDB-GENE-100105-2	Length:	475	Species:	Danio rerio

Alignment Length:	491	Identity:	124/491 - (25%)
Similarity:	212/491 - (43%)	Gaps:	80/491 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 ILEPAVFLIFFARNLIGAVYQNQILYQTCITIEKFNATQCEPLLGIDRGSDADKEVEVIVQTYSA 117
            ::||||.|..||..:...:.|..:..:....:..|..|. |.|      |........|  |...
Zfish     6 LIEPAVGLYAFAMFMFYPLLQQYVYRRLWFELSGFIYTS-ESL------SHCSSNHSYI--TLHQ 61

  Fly   118 NIMMTTS--LLES----IIPAFAS-LFLGPWSDKFGRRPILLTTFTGYLTGALILIVITYITRST 175
            .:...||  ||.|    :||:..| |.|..:||..||:..::....|....||..::::..:.|.
Zfish    62 AVQKETSLFLLHSELCFLIPSLISALLLVSYSDYCGRKVAIVPPLVGEALHALSYVLVSRFSFSL 126

  Fly   176 NISPWWFLLSSVPSVVSGGTCALITGIYCYISDVAKE--------RKKALRMVLNE----ASLCA 228
            |    :.|.||..|.:.||...||.|.:.|::|:..|        |...|.|:|..    ||||.
Zfish   127 N----YLLASSFMSGLMGGPPTLIGGCFAYVADLCGEDLEGQKTVRMARLDMILGVLTGLASLCT 187

  Fly   229 GIMVGNVASGYIYAATNALVLFSIAGSLMMFALMYVLLFVPESL-NPGD-IHTGS-------RVR 284
            |..:  .|:|:.:.       |..|..|.:..|:|||:.:.||| .|.. :.|.|       |:|
Zfish   188 GFFI--KAAGFTWP-------FLTAVFLHLINLLYVLVVLKESLVLPNSAVSTSSPSASEAPRLR 243

  Fly   285 EFFRFDLVTDLIRTCFK------RRPNFDRTIIWLTMIALTIAIFD--MEGESTVNYMFVQDKFN 341
            :       |..:.|..:      ...|..|.::.|.|:| ..|.|.  ::|..::   |:..:.|
Zfish   244 Q-------TQALTTRLQGVYLLFAASNRRRNVVLLLMLA-AFAFFKLALQGGWSI---FILYELN 297

  Fly   342 ----WTIKDFSLFNASRIVIQIVGSIVGMLVLRRVLKMS-IVTMAMLSLACCVLESTVRATAVYW 401
                |:.......:|....|.:| |..|:.:|.|.|..: |:.:.::|:|..::.:....|.:..
Zfish   298 TPLCWSEVFVGYGSALSTAIYLV-SFAGVALLSRCLPDAYIILLGLMSVAAGLIMAAFAKTTLLM 361

  Fly   402 QELYLGMTLGMMRGVMGPMCRAILSHVAPATEVGKIFALTTSMESVSPLGAAPLYTTVYKATLEN 466
            ..:.|.:.|.:|   ..|:.|:::|.:...:|.|.:||....:|.:|...:..::.::|.|||..
Zfish   362 FLVRLPLLLSIM---PTPVLRSMMSKIVSGSEQGAMFACVAFVEMLSVGVSFTVFNSIYAATLSW 423

  Fly   467 YPGAFNFISAA-LYFVCYILIAVIFGIQKSMGSSSV 501
            :.| |:|:.|| |..:...||.||..::..:...|:
Zfish   424 FSG-FSFLLAAGLTVIPSALICVILCLRLDVYEESI 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30344	NP_724759.1	MFS	113..490	CDD:119392	108/418 (26%)
CG30344	NP_724759.1	MFS_1	128..448	CDD:284993	89/358 (25%)
slc46a3	XP_009303566.1	MFS_1	77..409	CDD:284993	89/359 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6513
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.830