DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30344 and Slc46a2

DIOPT Version :9

Sequence 1:	NP_724759.1	Gene:	CG30344 / 246552	FlyBaseID:	FBgn0050344	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_066395.3	Gene:	Slc46a2 / 30936	MGIID:	1353616	Length:	479	Species:	Mus musculus

Alignment Length:	492	Identity:	100/492 - (20%)
Similarity:	201/492 - (40%)	Gaps:	94/492 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 SSYR---WFILEPAVFLIFFARNLIGAVYQNQILYQTCITIEKFNATQCEPLLGIDRGSDADKEV 108
            |.:|   |  :||.|    .:..:.|::|...:|   .:..|.|.:         :.|..::...
Mouse    14 SGFRVRTW--IEPVV----ASTQVAGSLYDAGLL---LVVKESFKS---------EAGGSSNYSA 60

  Fly   109 EVIVQTYS--------ANIMMTTSLLESIIPAFASLFLGPWSDKFGRRPILLTTFTGYL---TGA 162
            ...:..|.        :|..:..:|:..:.|..::..||..||::.|:..:.|...|:|   .|.
Mouse    61 NQSLVEYQEDQQQKAISNFNIIYNLVLGLTPLLSAYGLGWLSDRYHRKISICTAMLGFLLSRIGL 125

  Fly   163 LILIVITYITRSTNISPWWFLLSSVPSVVSGGTC----ALITGIYCYISDVAKERKKALRMVLNE 223
            |:.:::.           |.:.....:....|.|    |..:|:....|....|.::::|::|.:
Mouse   126 LLKVMLD-----------WPVEVMYGAAALNGLCGSFSAYWSGVMALGSLGCSEGRRSVRLILID 179

  Fly   224 ASLCAGIMVGNVASGYIYA-----ATNALVLFSIAGSLMMFALMYVL--LFVPESLNPGDIHTGS 281
            ..|......|::|||:::.     :...|:|.:.:.....|||.|.|  |.|||| .|..:|.
Mouse   180 LVLGLAGFSGSMASGHLFKQIVGHSAQGLLLTACSVGCAAFALFYSLFVLKVPES-KPNKVHP-- 241

  Fly   282 RVREFFRFDLVTDLIRTC------------FKRRP-------NFDRTIIWLTMIALTIAIFDMEG 327
                  ..|.|:.::.|.            ..|.|       :..|.::.|..:.  ..|:|:..
Mouse   242 ------TVDTVSGMMGTYRTLDPDQQDKQNVPRNPRTPGKGKSSQREVVALLFVG--AIIYDLAA 298

  Fly   328 ESTVNYM--FV-QDKFNWTIKDFSLFNASRIVIQIVGSIVGMLVLRRVLK-MSIVTMAMLSLAC- 387
            ..||:.|  || ::..:|.........||..:| .:.|.:|:||..|..: .:::.:.|||...
Mouse   299 VGTVDVMALFVLKEPLHWNQVQLGYGMASGYII-FITSFLGVLVFSRCFRDTTMIIIGMLSFGSG 362

  Fly   388 CVLESTVRATAVYWQELYLGMTLGMMRGVMGPMCRAILSHVAPATEVGKIFALTTSMESVSPLGA 452
            .:|.:.|:.|.::    |:...:.:...:.....|:.:|.:...:..||||.:.....:::.:..
Mouse   363 ALLLAFVKETYMF----YIARAIMLFALIPITTIRSAMSKLIKDSSYGKIFVILQLCLTLTGVVT 423

  Fly   453 APLYTTVYKATLENYPGAFNFISAALYFVCYILIAVI 489
            :.:|..:|:.||:.:.|....:|:.|.|:..:.|.|:
Mouse   424 STIYNKIYQLTLDKFIGTCFVLSSFLSFLAIVPIGVV 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30344	NP_724759.1	MFS	113..490	CDD:119392	88/423 (21%)
CG30344	NP_724759.1	MFS_1	128..448	CDD:284993	75/357 (21%)
Slc46a2	NP_066395.3	MFS	86..455	CDD:119392	83/395 (21%)
		MFS_1	88..422	CDD:284993	75/360 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	255..277		2/21 (10%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844273
Domainoid	1	1.000	70	1.000	Domainoid score	I9497
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8701
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840