DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30344 and Slc46a1

DIOPT Version :9

Sequence 1:	NP_724759.1	Gene:	CG30344 / 246552	FlyBaseID:	FBgn0050344	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001013991.1	Gene:	Slc46a1 / 303333	RGDID:	1309472	Length:	459	Species:	Rattus norvegicus

Alignment Length:	441	Identity:	106/441 - (24%)
Similarity:	194/441 - (43%)	Gaps:	27/441 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LEPAVFLIFFARNLIGAVYQNQILYQTCITIEKFNATQCEPLLGIDRGSDADKEVEVIVQTYSAN 118
            :||.|||..||..|.|.: ..|.::....|...:|.|:.....|........||||    |.:::
  Rat    25 VEPLVFLANFALVLQGPL-TTQYIWHRISTELGYNGTRHRENCGNQSADPVLKEVE----TLTSH 84

  Fly   119 IMMTTSLLESIIPAFASLFLGPWSDKFGRRPILLTTFTGYLTGALILIVITYITRSTNISPWWFL 183
            ..:..::...::..|.|..||.|||:.||||:|:....|.|..|::.|.:..:    .:...:|:
  Rat    85 WTLYMNVGGFLVGLFWSTLLGAWSDRVGRRPLLVLASLGLLLQAVVSIFVVQL----QLHIGFFV 145

  Fly   184 LSSVPSVVSGGTCALITGIYCYISDVAKERKKALRMVLNEASLCAGIMVGNVAS---GYIYAATN 245
            |......:.|....|:...:..::||:....:..||.|.||  |.|: .|.:||   |:...|..
  Rat   146 LGRALCALLGDFNGLLAASFASVADVSSNHSRTFRMALLEA--CIGV-AGTLASLLGGHWLRAQG 207

  Fly   246 ALVLFSIAGSLMMFALMYVLLFVPESLNPGDIHTGSRVREFFRFDLVTDLIRTCFKRRPNFDRTI 310
            ....|.:|.::::...:|......|::..      .:....|.......:::......|...|..
  Rat   208 YANPFWLALAVLIVMTLYAAFCFGETVKE------PKSTRLFTLRHHRSIVQLYVVPAPEKSRMH 266

  Fly   311 IWLTMIALTIAIFDMEGESTVNYMF-VQDKFNWTIKDFSLFNASRIVIQIVGSIVGMLVLRRVLK 374
            :.|..:|:.:.:....|...:..:: :.....|..|.....:|:: .:..:.|::|:.:|:..|.
  Rat   267 LALYSLAIFVVVTVHFGAQDILTLYELSTPLCWDSKLIGYGSAAQ-HLPYLTSLLGLRLLQFCLA 330

  Fly   375 MSIVTMAMLSLACCVLESTVRATAVYWQELYLGMTLGMMRGVMGPMCRAILSHVAPATEVGKIFA 439
            .:.|  |.:.||..:|...|.|.|.....::.|..|..:..|..|:.||.||.:...:|.|.:|:
  Rat   331 DTWV--AEIGLAFNILGMVVFAFATITPLMFTGYGLLFLSLVTTPVIRAKLSKLVSESEQGALFS 393

  Fly   440 LTTSMESVSPLGAAPLYTTVYKATLENYPGAFNF-ISAALYFVCYILIAVI 489
            ....:.|::.|.|:.::.::|.||| |:...|.| :.|.|.|:..|||.|:
  Rat   394 AVACVNSLAMLMASGIFNSLYPATL-NFMKGFPFLLGAGLLFIPAILIGVL 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30344	NP_724759.1	MFS	113..490	CDD:119392	88/382 (23%)
CG30344	NP_724759.1	MFS_1	128..448	CDD:284993	71/323 (22%)
Slc46a1	NP_001013991.1	MFS	22..444	CDD:421695	106/441 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I6433
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	126	1.000	Inparanoid score	I4593
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44504
orthoMCL	1	0.900	-	-		OOG6_100739
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.880