DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30344 and AgaP_AGAP003000

DIOPT Version :9

Sequence 1:	NP_724759.1	Gene:	CG30344 / 246552	FlyBaseID:	FBgn0050344	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_311884.5	Gene:	AgaP_AGAP003000 / 1272954	VectorBaseID:	AGAP003000	Length:	524	Species:	Anopheles gambiae

Alignment Length:	501	Identity:	124/501 - (24%)
Similarity:	227/501 - (45%)	Gaps:	55/501 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 TGEDSAPRILDASSAASSEQVDPPPVPPPHDYSSYRWF---ILEPAVFLIFFARNLIGAVYQNQI 76
            :||.|.|...:...|.||.........   ...:.||:   .:||::||...|..|...|.|...
Mosquito    11 SGEHSQPGAQEDGDAGSSNVAGAMATA---SVRAERWYEKISVEPSMFLYMMAFMLTSVVEQAFF 72

  Fly    77 LYQTCITIEKFNATQCEPLLGIDRGSDADKEVEVIVQTYSA--NIMMTTSLLESIIPAFASLFLG 139
            ||:.|.....::...|   |.|::..|..|:|:|...|:..  ||.|      .::|...:||||
Mosquito    73 LYKACTVDHGYSHEIC---LNIEQYQDIKKQVQVTTSTFHQWNNIAM------YVVPIVLALFLG 128

  Fly   140 PWSDKFGRRPILLTTFTGYLTGALILIVITYITRSTNISPWW-----FLLSSVPSVVSGGTCALI 199
            .|||:.||:..|:....|....:::::|.|.:       |.|     ...:::|||::|...|:.
Mosquito   129 AWSDRRGRKLPLILGLMGKFVYSVMIVVNTRM-------PSWPVEYIIYTATIPSVLTGADIAIF 186

  Fly   200 TGIYCYISDVAKERKKALRMVLNEASLCA----GIMVGNVASGYIYAATNALVLFSIAGSLMMFA 260
            ...:.||||:....::.||:.:.:|:..:    |:.:|||.  :.:...:..::|.|..||:..:
Mosquito   187 ASCFAYISDITTVEERTLRITILDATYLSTMPIGVALGNVI--FNHTGKSYTIMFIINASLLACS 249

  Fly   261 LMYVLLFVPESLNPGDIHTGSRVRE---------FFRFDLVTDLIRTCFKRRPNFDRTIIWLTMI 316
            ::|.:|    .|..........:||         ||....|...:||..:||....||.::|.|:
Mosquito   250 IVYSML----RLKSRTTERQCSIRELPWYRMPLDFFDRQHVVRSVRTFVRRRTMHRRTYMYLLMV 310

  Fly   317 ALTIAIFDMEGESTVNYMFVQDKFNWTIKDFSLFNASRIVIQIVGSIVGMLVLRRVLKMSIVTMA 381
            |::...|..: |....|::.|.:|||....:|.|...:....:|...:|:.:..:||.:....:.
Mosquito   311 AMSFYTFQRD-EKPKMYLYTQLRFNWDTDLYSYFKTYQSAAYVVMMFLGVPLFTKVLGLKDTLII 374

  Fly   382 MLSLACCVLESTVRATAVYWQ---ELYLGMTLGMMRGVMGPMCRAILSHVAPATEVGKIFALTTS 443
            |:.   .:..::.|...::.|   .||:|.|:..:..|:.|:.|:::|.:.|..|.|.||:..:.
Mosquito   375 MIG---ALAHASARFVYIFAQVGWVLYIGATISSVGPVVAPVLRSMISKMVPTNERGIIFSFLSV 436

  Fly   444 MESVSPLGAAPLYTTVYKATLENYPGAFNFISAALYFVCYILIAVI 489
            .::..||.:..|||.||.:::..||.|...::.....:.:.:...|
Mosquito   437 FDNAVPLFSGVLYTQVYNSSINTYPQAIFLLTMGTQMIVFFIALAI 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30344	NP_724759.1	MFS	113..490	CDD:119392	97/400 (24%)
CG30344	NP_724759.1	MFS_1	128..448	CDD:284993	82/340 (24%)
AgaP_AGAP003000	XP_311884.5	MFS	110..478	CDD:119392	95/390 (24%)
AgaP_AGAP003000	XP_311884.5	MFS_1	110..437	CDD:284993	85/349 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X552
TreeFam	0	0.000	Not matched by this tool.
	6	5.830