DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30344 and Mfsd14a

DIOPT Version :9

Sequence 1:	NP_724759.1	Gene:	CG30344 / 246552	FlyBaseID:	FBgn0050344	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001316129.1	Gene:	Mfsd14a / 103689987	RGDID:	9294064	Length:	490	Species:	Rattus norvegicus

Alignment Length:	458	Identity:	86/458 - (18%)
Similarity:	171/458 - (37%)	Gaps:	137/458 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 VFLIFFARNLIGAVYQNQILYQTCITIEKFNATQCEPLLGIDRGSDADKEVEVIVQTYSANIMMT 122
            :||.|||..|:.|                       |.|            .|:.:|:..:..:.
  Rat    44 IFLEFFAWGLLTA-----------------------PTL------------VVLHETFPKHTFLM 73

  Fly   123 TSLLESI--IPAFASL-FLGPWSDKFGRRPILLTTFTGYLTGALILIVITYITRSTNISPWWFLL 184
            ..|::.:  :.:|.|. .:|..||.:||:..||.|.  :.|.|.|.::        .|||||:.
  Rat    74 NGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTV--FFTCAPIPLM--------KISPWWYF- 127

  Fly   185 SSVPSVVSGGTCALITGIYCYISDVAKERKKALRMVLNEASLCAGIMVGNVASGYIYAATNALVL 249
             :|.| |||......:.::.|::|:.:|.::::...|..|:..|.::.......|:.......::
  Rat   128 -AVIS-VSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGRVYGDSLV 190

  Fly   250 FSIAGSLMMFALMYVLLFVPESLNPGDIHTGSRVREFFRFDLVTDLIRTCFKRRP-NFDRTIIW- 312
            ..:|.::.:..:.::|:.|||||..                          |.|| ::...|.|
  Rat   191 VVLATAIALLDICFILVAVPESLPE--------------------------KMRPASWGAPISWE 229

  Fly   313 ------------------LTMIALTIAIFDMEGESTVNYMFVQDKFNWTIKDFSLFNASRIVIQI 359
                              |..|.:.::.....|:.:..:::::....::.:..:.|.|...::.|
  Rat   230 QADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFSPESVAAFIAVLGILSI 294

  Fly   360 VG-SIVGMLVLRRVLKMSIVTMAMLSLACCVLESTVRATAVY------WQELYLGMTLGMMRGVM 417
            :. :||..|::|.:...:.:   :|.|...:|:     .|.|      |. ::....:..|..:.
  Rat   295 IAQTIVLSLLMRSIGNKNTI---LLGLGFQILQ-----LAWYGFGSEPWM-MWAAGAVAAMSSIT 350

  Fly   418 GPMCRAILSHVAPATEVGKIFALTTSMESVSPLGAAPLYTTVYKATLENYPGAFNFISAALY-FV 481
            .|...|::|..|.|.:.|.:..:.|.:.                       |..|.:..||| |:
  Rat   351 FPAVSALVSRTADADQQGVVQGMITGIR-----------------------GLCNGLGPALYGFI 392

  Fly   482 CYI 484
            .||
  Rat   393 FYI 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30344	NP_724759.1	MFS	113..490	CDD:119392	76/403 (19%)
CG30344	NP_724759.1	MFS_1	128..448	CDD:284993	66/349 (19%)
Mfsd14a	NP_001316129.1	MFS	40..397	CDD:119392	86/458 (19%)
Mfsd14a	NP_001316129.1	MFS_1	42..386	CDD:284993	80/447 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810