DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30344 and slc46a1

DIOPT Version :9

Sequence 1:	NP_724759.1	Gene:	CG30344 / 246552	FlyBaseID:	FBgn0050344	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001120610.1	Gene:	slc46a1 / 100145771	XenbaseID:	XB-GENE-961470	Length:	462	Species:	Xenopus tropicalis

Alignment Length:	463	Identity:	117/463 - (25%)
Similarity:	209/463 - (45%)	Gaps:	50/463 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LEPAVFLIFFARNLIGAVYQNQILYQTCITIEKFNATQCEPLLGID---RGSDADKEVEVIVQTY 115
            :||.:||..||..|.|.: ..|.|:........||.|:.     :|   .||.:...::..|:|.
Frog    26 VEPVLFLSMFALALQGPL-TTQYLWDRLSADIGFNGTRI-----LDCTVNGSKSTGALQQEVETL 84

  Fly   116 SANIMMTTSLLESIIPAFASLFLGPWSDKFGRRPILLTTFTGYLTGALILIVITYITRSTNISPW 180
            :::..:..:|...::..|:.:.|||||||.||||:|.....|....|.:.:|:.|  :..:::
Frog    85 TSHWSLYINLGGFLVGLFSVMLLGPWSDKVGRRPVLFFPCIGLALQAALYLVVMY--QELHVA-- 145

  Fly   181 WFLLSSVPSVVSGGTCALITGIYCYISDVAKERKKALRMVLNEASLCAGI--MVGNVASGYIYAA 243
            :||:....|.:||....::.|.:.||:||:..:.:..|:.:.||  |.||  ||.::..|:...|
Frog   146 YFLIGRFISGISGDFNMILAGCFAYIADVSDRQSRTFRVAILEA--CLGIAGMVASIIGGHWRKA 208

  Fly   244 TNALVLFSIAGSLMMFALMYVLLFVPESL---NPGDIHTGSRVREFFRFDLVTDLIRTCFKRRPN 305
            ...:..|.:..::.:|..:||...|.||:   .|..:.|....:.|||...|:.         .|
Frog   209 QGYINPFWLVFAVNLFTAVYVYFCVEESVKDKKPARLFTHRHYQTFFRLFTVSG---------EN 264

  Fly   306 FDRTIIWLTMIALTIAIFDMEGESTVNYMFVQDKFNWTI---KDFSLFNASRIVIQIVGSIVGML 367
            ..|..:.|..:||.:.:....|...   :||..:.::.:   .|...:.::...:..:.|:.|:.
Frog   265 NRRRKLCLYSLALLVVVTVHMGAKN---LFVLYELSYPLCWDSDLIGYGSAAEHLTYLSSLAGLR 326

  Fly   368 VLRRVLKMS-IVTMAMLS-LACCVLESTVRATAVYWQELYLGMTLGMMRGVMGPMCRAILSHVAP 430
            :.:..|..| :..|..:| ::..|:.|....|.|    ::.|..|........|:.|:.||.:..
Frog   327 LFQLCLADSWVAEMGFISNISGLVVISLASTTPV----MFTGYGLRFFAMATTPVIRSKLSKMVE 387

  Fly   431 ATEVGKIFALTTSMESVSPLGAAPLYTTVYKATLENYPGAFNFISAALYFVCYILIAVIFGI--- 492
            ..|.|.:|:....:|.:|.|.|..::.::|.|||....| |.|:..||..   ::.|.|.|:
Frog   388 EGEQGALFSSVACVEGLSYLLATAVFNSLYPATLHFMQG-FPFLFGALLL---LIPAGIIGLIEV 448

  Fly   493 --QKSMGS 498
              ||.|.|
Frog   449 CDQKPMYS 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30344	NP_724759.1	MFS	113..490	CDD:119392	94/386 (24%)
CG30344	NP_724759.1	MFS_1	128..448	CDD:284993	79/329 (24%)
slc46a1	NP_001120610.1	MFS	79..446	CDD:119392	97/392 (25%)
slc46a1	NP_001120610.1	MFS_1	97..410	CDD:284993	81/334 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	97	1.000	Domainoid score	I7096
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4704
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47543
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060