DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30340 and Npffr2

DIOPT Version :9

Sequence 1:	NP_724812.2	Gene:	CG30340 / 246550	FlyBaseID:	FBgn0050340	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_076470.1	Gene:	Npffr2 / 78964	RGDID:	620168	Length:	417	Species:	Rattus norvegicus

Alignment Length:	353	Identity:	90/353 - (25%)
Similarity:	157/353 - (44%)	Gaps:	61/353 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DDFDFGKWDFPAERIW---------------------LHKPNGEITWKICTFLPLIAFGLYGNFS 51
            |....|.||    .||                     ||:|:....: |.::..:....:.||..
  Rat     6 DSNSSGSWD----HIWSGNDTQHPWYSDINITYMNYYLHQPHVTAVF-ISSYFLIFFLCMVGNTV 65

  Fly    52 MVYVIATNRSLRSPTNLIIANMAVADLLTLAICPAMFMVNDFYQNYQLGCVGCKLEGFLVVVFLI 116
            :.:|:..||.:.:.||..|.|:|::|||....|..:.::::....:..|...||:.|.:..:.:.
  Rat    66 VCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVA 130

  Fly   117 TAVLNLSVVSYDRLTAIVLPMETRLTIRGVQIVVVCTWVSGILLASPLAFY------RSYRVRVW 175
            .:|..|..::.||...:|.|.:.:||::...:::|..|...|.:.:|.|..      :.||||:.
  Rat   131 ASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVMIVIIWGLAITIMTPSAIMLHVQEEKYYRVRLS 195

  Fly   176 ---KNFTERYCKE---NTSVLPKYWYVLITILVWLPLGIMLICYIAIFYKL----------DRYE 224
               |..|..:|:|   |..:...|..||...:...||.:::|.|..|...|          .|.|
  Rat   196 SHNKTSTVYWCREDWPNQEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTSAHSTGKQRLE 260

  Fly   225 KRVLSRENPLTVSYKRSVAKTLFIVVVVFAALRLPFTILVVLREKYFGEDVSVSSGMQLFWYI-- 287
            :..:|::       |:.|.|.|..|.::|....||...|::|.:.   .|:|.:....:..|:
  Rat   261 QWHVSKK-------KQKVIKMLLTVALLFILSWLPLWTLMMLSDY---ADLSPNKLRVINIYVYP 315

  Fly   288 -SQYLMFLNAAVNPLIYGFNNENFRRAY 314
             :.:|.|.|::|||:||||.|||||..:
  Rat   316 FAHWLAFCNSSVNPIIYGFFNENFRSGF 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30340	NP_724812.2	7tm_4	44..315	CDD:304433	80/296 (27%)
CG30340	NP_724812.2	7tm_1	48..303	CDD:278431	71/279 (25%)
Npffr2	NP_076470.1	7tm_4	53..>176	CDD:304433	29/122 (24%)
		7tm_1	62..332	CDD:278431	71/279 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	378..417
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1308959at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920