DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30340 and NPFFR1

DIOPT Version :9

Sequence 1:NP_724812.2 Gene:CG30340 / 246550 FlyBaseID:FBgn0050340 Length:396 Species:Drosophila melanogaster
Sequence 2:NP_071429.1 Gene:NPFFR1 / 64106 HGNCID:17425 Length:430 Species:Homo sapiens


Alignment Length:306 Identity:75/306 - (24%)
Similarity:134/306 - (43%) Gaps:44/306 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 LIAFGL------YGNFSMVYVIATNRSLRSPTNLIIANMAVADLLTLAICPAMFMVNDFYQNYQL 99
            ::|:.|      .||..:.:::..||.:.:.||:.|.|:||:|||....|....:|::....:..
Human    47 IVAYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPF 111

  Fly   100 GCVGCKLEGFLVVVFLITAVLNLSVVSYDRLTAIVLPMETRLTIRGVQIVVVCTWVSGILLASPL 164
            ....||:.|.:..:.:..:|..|..::.:|...||.|...:||:|...:.:...|...:|:..|.
Human   112 DNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPS 176

  Fly   165 AF----------------YRSYRV-RVWKNFTERYCKENTSVLPKYWYVLITILVWLPLGIMLIC 212
            |.                .|||.: ..|:.:.|:..:.      .|..||.:.:...||.::::.
Human   177 AVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRR------VYTTVLFSHIYLAPLALIVVM 235

  Fly   213 YIAIFYKLDRYEKRVLSRE---NPLTVSYKRSVAKTLFIVVVVFAALRLPFTILVVLREKYFGED 274
            |..|..||.:........|   :|.....:..|...|.:|.:.|....||...|::|.:  :|: 
Human   236 YARIARKLCQAPGPAPGGEEAADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLID--YGQ- 297

  Fly   275 VSVSSGMQLF------WYISQYLMFLNAAVNPLIYGFNNENFRRAY 314
               .|..||.      :..:.:|.|.|::.||:|||:.||||||.:
Human   298 ---LSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGF 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30340NP_724812.2 7tm_4 44..315 CDD:304433 74/303 (24%)
7tm_1 48..303 CDD:278431 64/280 (23%)
NPFFR1NP_071429.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
7tm_GPCRs 44..340 CDD:333717 75/304 (25%)
TM helix 1 46..70 CDD:320095 4/22 (18%)
TM helix 2 79..101 CDD:320095 9/21 (43%)
TM helix 3 117..139 CDD:320095 4/21 (19%)
TM helix 4 160..176 CDD:320095 2/15 (13%)
TM helix 5 214..237 CDD:320095 5/28 (18%)
TM helix 6 266..291 CDD:320095 7/24 (29%)
TM helix 7 308..333 CDD:320095 8/24 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 379..413
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1308959at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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