DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30340 and NPY2R

DIOPT Version :9

Sequence 1:NP_724812.2 Gene:CG30340 / 246550 FlyBaseID:FBgn0050340 Length:396 Species:Drosophila melanogaster
Sequence 2:NP_000901.1 Gene:NPY2R / 4887 HGNCID:7957 Length:381 Species:Homo sapiens


Alignment Length:309 Identity:92/309 - (29%)
Similarity:145/309 - (46%) Gaps:55/309 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 ICTFLPLIAFGLYGNFSMVYVIATNRSLRSPTNLIIANMAVADLLTLAICPAMFMVNDFYQNYQL 99
            |..:..:|..|:.||..:::|:...:|:|:.||..|||:||||||...:|....:.......:::
Human    54 ILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKM 118

  Fly   100 GCVGCKL----EGFLVVVFLITAVLNLSVVSYDRLTAIVLPMETRLTIRGVQIVVVCTWVSGILL 160
            |.|.|.|    :|..|.|..||    |:|::.||...||..:|::::.|...:::...|....||
Human   119 GPVLCHLVPYAQGLAVQVSTIT----LTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALL 179

  Fly   161 ASPLAFYRSYR-VRVWKNF-----TERYCKENTSVL-PKYWYVLITILVWLPLGIMLICYIAIFY 218
            |||||.:|.|. :.:..:|     ||::..|..|:. ..|....:.||..|||||:...|..|:.
Human   180 ASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWS 244

  Fly   219 KL----------DRYEKRVLSRENPLTVSYKRSVAKTLFIVVVVFAALRLP---FTILV-----V 265
            ||          |.|.:|            ::...|.|..||||||...||   |.:.|     |
Human   245 KLKNHVSPGAANDHYHQR------------RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQV 297

  Fly   266 LREKYFGEDVSVSSGMQLFWYISQYLMFLNAAVNPLIYGFNNENFRRAY 314
            |..|.:          :|.:.:...:...:...|||:||:.|.|:|:|:
Human   298 LDLKEY----------KLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAF 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30340NP_724812.2 7tm_4 44..315 CDD:304433 90/300 (30%)
7tm_1 48..303 CDD:278431 83/283 (29%)
NPY2RNP_000901.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35
7tmA_NPY2R 51..336 CDD:320521 91/307 (30%)
TM helix 1 52..78 CDD:320521 6/23 (26%)
TM helix 2 85..110 CDD:320521 12/24 (50%)
TM helix 3 123..153 CDD:320521 11/33 (33%)
TM helix 4 164..185 CDD:320521 7/20 (35%)
TM helix 5 216..245 CDD:320521 10/28 (36%)
TM helix 6 261..291 CDD:320521 12/41 (29%)
TM helix 7 304..329 CDD:320521 6/24 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24235
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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