DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30340 and Npy1r

DIOPT Version :9

Sequence 1:	NP_724812.2	Gene:	CG30340 / 246550	FlyBaseID:	FBgn0050340	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001345884.1	Gene:	Npy1r / 18166	MGIID:	104963	Length:	382	Species:	Mus musculus

Alignment Length:	305	Identity:	75/305 - (24%)
Similarity:	136/305 - (44%)	Gaps:	26/305 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 HKPNGEITWKICTFLPLIAFGLYGNFSMVYVIATNRSLRSPTNLIIANMAVADLLTLAICPAMFM 89
            |.|...|......:..:|..|:.||.:::.:|...:.:|:.||::|.|::.:|||...:|.....
Mouse    33 HLPLAVIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAVMCLPFTF 97

  Fly    90 VNDFYQNYQLGCVGCKLEGFLVVVFLITAVLNLSVVSYDRLTAIVLPMETRLTIRGVQIVVVCTW 154
            |.....::..|...|||..|:..|.:..::.:|.:::.:|...|:.|...|...|...|.:...|
Mouse    98 VYTLMDHWVFGETMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYIGITVIW 162

  Fly   155 VSGILLASPLAFYRSYRVRVWKN-----FTERY-CKE---NTSVLPKYWYVLITILVWLPLGIML 210
            |..:..:.|...|:......::|     |.::| |.:   :.|....|..:|:.:..:.||..:.
Mouse   163 VLAVASSLPFVIYQILTDEPFQNVSLAAFKDKYVCFDKFPSDSHRLSYTTLLLVLQYFGPLCFIF 227

  Fly   211 ICYIAIFYKLDRYEKRVLSRENPL----TVSYKRSVAKTLFI----VVVVFAALRLPFTILVVLR 267
            |||..|:.:|.|       |.|.:    ...|:.|..|.:.|    :||.||...||.||...:.
Mouse   228 ICYFKIYIRLKR-------RNNMMDKIRDSKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVF 285

  Fly   268 EKYFGEDVSVSSGMQLFWYISQYLMFLNAAVNPLIYGFNNENFRR 312
            :  :...:..:....|.:.:......::..|||:.|||.|:||:|
Mouse   286 D--WNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQR 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30340	NP_724812.2	7tm_4	44..315	CDD:304433	71/286 (25%)
CG30340	NP_724812.2	7tm_1	48..303	CDD:278431	63/271 (23%)
Npy1r	NP_001345884.1	7tmA_NPY1R	40..330	CDD:320517	72/298 (24%)
		TM helix 1	42..66	CDD:320517	5/23 (22%)
		TM helix 2	75..97	CDD:320517	7/21 (33%)
		TM helix 3	113..135	CDD:320517	5/21 (24%)
		TM helix 4	156..172	CDD:320517	3/15 (20%)
		TM helix 5	208..231	CDD:320517	6/22 (27%)
		TM helix 6	261..283	CDD:320517	9/21 (43%)
		TM helix 7	298..323	CDD:320517	7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010