DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30340 and npffr2

DIOPT Version :9

Sequence 1:	NP_724812.2	Gene:	CG30340 / 246550	FlyBaseID:	FBgn0050340	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_002940397.1	Gene:	npffr2 / 100498122	XenbaseID:	XB-GENE-994428	Length:	426	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	96/372 - (25%)
Similarity:	181/372 - (48%)	Gaps:	23/372 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 WLHKPNGEITWKICTFLPLIAFGLYGNFSMVYVIATNRSLRSPTNLIIANMAVADLLTLAICPAM 87
            :||:|:....: |.::|.:....:.||..:.:::.:::.:|:.|||.|.|:|::|||....|...
Frog    36 YLHRPSVAAVF-IASYLLIFILCMLGNGVVCFIVLSSKHMRTVTNLFILNLAISDLLVGIFCMPT 99

  Fly    88 FMVNDFYQNYQLGCVGCKLEGFLVVVFLITAVLNLSVVSYDRLTAIVLPMETRLTIRGVQIVVVC 152
            .::::....:..|...||:.|.:..:.:..:|..|..::.||...||.|.:.:|||....:::|.
Frog   100 TLLDNIIAGWPFGSTVCKMSGMVQGISVSASVFTLVAIAVDRFRCIVYPFKQKLTISTAVVIIVV 164

  Fly   153 TWVSGILLASPLAFY------RSYRVRVW-KNFTE--RYCKE---NTSVLPKYWYVLITILVWLP 205
            .||..|.:..|.|..      :::||.:. .|.|.  .:|:|   |..:...|..||.:.:...|
Frog   165 IWVLAIAIMCPSAVMSHVKEDKNFRVVIGNSNQTNPIYWCREDWPNPEMRKIYTTVLFSNIYLAP 229

  Fly   206 LGIMLICYIAIFYKLDRYEKRVLSRENPL---TVS-YKRSVAKTLFIVVVVFAALRLPFTILVVL 266
            |.:::|.|..|...|.:.|..|.::.:..   .|| .|:.|.|.|.|:.::|....||...|::|
Frog   230 LSLIVIMYARIGITLFKSELNVENKNHQQPRHAVSRRKQKVIKMLIIIALLFILSWLPLWTLMML 294

  Fly   267 REKYFGEDVSVSSGMQLFWY-ISQYLMFLNAAVNPLIYGFNNENFRRAYYQISWVRRWRDATQMK 330
            .: |.....:....:.::.| .:.:|.|.|:::||:||||.||||||.:.....::...:..:.:
Frog   295 TD-YANLTQNQYQMINIYIYPFAHWLAFFNSSINPIIYGFFNENFRRGFQAAFKLQLCSEELERR 358

  Fly   331 KF--SRSPDHCCYCAFMKNGKRTSEAAQK--AGNLEKDISKDMSSAQ 373
            ..  .|:..:....|...|..|.:.|.:|  :.:.|.|..|.::|.|
Frog   359 TMYSHRAQGNAILPAASHNTARQNSAFEKQSSDDKESDKRKPLTSDQ 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30340	NP_724812.2	7tm_4	44..315	CDD:304433	80/287 (28%)
CG30340	NP_724812.2	7tm_1	48..303	CDD:278431	70/271 (26%)
npffr2	XP_002940397.1	7tmA_NPFFR2	44..342	CDD:320646	82/299 (27%)
		TM helix 1	45..71	CDD:320646	4/26 (15%)
		TM helix 2	78..104	CDD:320646	10/25 (40%)
		TM helix 3	116..146	CDD:320646	7/29 (24%)
		TM helix 4	157..178	CDD:320646	5/20 (25%)
		TM helix 5	214..243	CDD:320646	8/28 (29%)
		TM helix 6	265..295	CDD:320646	9/29 (31%)
		TM helix 7	310..335	CDD:320646	10/24 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1308959at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010