DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30339 and Sec14l1

DIOPT Version :9

Sequence 1:	NP_724813.1	Gene:	CG30339 / 246549	FlyBaseID:	FBgn0050339	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_083053.2	Gene:	Sec14l1 / 74136	MGIID:	1921386	Length:	719	Species:	Mus musculus

Alignment Length:	255	Identity:	47/255 - (18%)
Similarity:	91/255 - (35%)	Gaps:	65/255 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LRDWLAKQPHLRARQDDQFLVGFLRGCKFSLEKTKSKLDHFYTIKTLMPELFGKRLVDERNLILC 97
            ||.|| ::.|......|:.::.|||...|:::|.:.                          |:|
Mouse   262 LRQWL-QETHKGKIPKDEHILRFLRARDFNIDKARE--------------------------IMC 299

  Fly    98 RSGTYVR------LPKPW-----------------GTDGPRLQLTNYEKFDPKEF-KLLD---LF 135
            :|.|:.:      :...|                 ..||..|.:....:.|.|.. :.|.   |.
Mouse   300 QSLTWRKQHQVDYILDTWTPPQVLLDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALL 364

  Fly   136 RYQTMITEQSIREDDHSN------ISGYVEIVDMAKMSLSFLAQLDFTLIKRMGIFAEKAQPTRL 194
            ||...|.|:.:|..:.:.      ||.:..:||:..:::..|.:.....:.|:....|...|..|
Mouse   365 RYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETL 429

  Fly   195 KGVHLINCPKEGVALLNLAKSLMPSKLQQRFHVYKNLEQ-----LNEVIPREYLPEEYGG 249
            ..:.::..|:....|..|....:....:::|.:|...:.     |.:.|.:|.:|:...|
Mouse   430 GRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSG 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30339	NP_724813.1	CRAL_TRIO_N	28..70	CDD:215024	11/36 (31%)
CG30339	NP_724813.1	CRAL_TRIO	109..250	CDD:279044	32/173 (18%)
Sec14l1	NP_083053.2	Required for interaction and inhibitory function toward DDX58. /evidence=ECO:0000250\|UniProtKB:Q92503	1..510		47/255 (18%)
		PRELI	17..173	CDD:282550
		CRAL_TRIO_N	256..301	CDD:215024	13/65 (20%)
		CRAL_TRIO	326..490	CDD:279044	31/164 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810