DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30339 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_724813.1	Gene:	CG30339 / 246549	FlyBaseID:	FBgn0050339	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_653103.1	Gene:	Sec14l2 / 67815	MGIID:	1915065	Length:	403	Species:	Mus musculus

Alignment Length:	294	Identity:	67/294 - (22%)
Similarity:	113/294 - (38%)	Gaps:	62/294 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EERVPADLKALRDWLAKQPHLRARQDDQFLVGFLRGCKFSLEKTKSKL----------DHFYTIK 77
            ||.:....:.::|.|...|:    .||.||:.:||...|.|:|:::.|          |....|.
Mouse    13 EEALAKFRENVQDVLPTLPN----PDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDKIIS 73

  Fly    78 TLMPELFGKRLVDERNLILCRSGTYVRLPKPWGTDGPRLQLTNYEKFDPKEFKLL-------DLF 135
            ...||:..:.|...|    |          .:..||..:.   |:...|.:.|.|       ||.
Mouse    74 WQPPEVIQQYLSGGR----C----------GYDLDGCPVW---YDIIGPLDAKGLLFSASKQDLL 121

  Fly   136 RYQ----TMITEQSIREDDH--SNISGYVEIVDMAKMSLSFLAQLDFTLIKRMGIFA---EKAQP 191
            |.:    .::.::.|::...  ..|.....|.|...:.|..|.:   ..::..|.|.   |:..|
Mouse   122 RTKMRDCELLLQECIQQTTKLGKKIETITMIYDCEGLGLKHLWK---PAVEAYGEFLTMFEENYP 183

  Fly   192 TRLKGVHLINCPKEGVALLNLAKSLMPSKLQQRFHV----YKNLEQLNEVIPREYLPEEYGGNNG 252
            ..||.:.::..||......||.|..:....:::..|    :|  |.|.:.|..:.||.||||.
Mouse   184 ETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRRKIMVLGANWK--EVLLKHISPDQLPVEYGGT-- 244

  Fly   253 RIADIQAEAEKKLLSYESYFAE-DSQYGVDEQLR 285
             :.|  .:...|..|..:|..: ..||.|.:|::
Mouse   245 -MTD--PDGNPKCKSKINYGGDIPKQYYVRDQVK 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30339	NP_724813.1	CRAL_TRIO_N	28..70	CDD:215024	12/41 (29%)
CG30339	NP_724813.1	CRAL_TRIO	109..250	CDD:279044	36/160 (23%)
Sec14l2	NP_653103.1	CRAL_TRIO_N	13..59	CDD:215024	15/49 (31%)
		SEC14	76..244	CDD:214706	41/189 (22%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810