DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30339 and Sec14l4

DIOPT Version :9

Sequence 1:	NP_724813.1	Gene:	CG30339 / 246549	FlyBaseID:	FBgn0050339	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001102560.1	Gene:	Sec14l4 / 498399	RGDID:	1565810	Length:	412	Species:	Rattus norvegicus

Alignment Length:	309	Identity:	73/309 - (23%)
Similarity:	121/309 - (39%)	Gaps:	60/309 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MANLRPLSAELRRIAETELNEVEERVPADLKALRDWLAKQPHLRARQDDQFLVGFLRGCKFSLEK 65
            :.:|.|...|    |.|...|:          |:|.|...|    :.||.||:.:||...|.|:|
  Rat     5 VGDLSPQQQE----ALTRFREI----------LQDVLPTLP----KADDFFLLRWLRARNFDLKK 51

  Fly    66 T------------KSKLDHFYTIKTLMPELFGKRLVDERNLILCRSGTYVRLPKPW----GTDGP 114
            :            :..|||..|.:.  ||:.  ||.|...  || ...|...| .|    ||..|
  Rat    52 SEDMLRKHVEFRNQQDLDHILTWQP--PEVI--RLYDSGG--LC-GYDYEGCP-VWFDLIGTLDP 108

  Fly   115 RLQLTNYEKFD--PKEFKLLDLFRYQTMITEQSIREDDHSNISGYVEIVDMAKMSLSFLAQLDFT 177
            :....:..|.|  .|..|:.::..::..:..|.:..    .:...|.:.||..:||..|.:....
  Rat   109 KGLFMSASKQDLIRKRIKVCEMLLHECELQSQKLGR----KVERMVMVFDMEGLSLRHLWKPAVE 169

  Fly   178 LIKRMGIFAEKAQPTRLKGVHLINCPKEGVALLNLAKSLMPSKLQQRFHV----YKNLEQLNEVI 238
            :.::.....|...|..:|.:.:|..||......||.||.:....|::..:    :|  ::|.:.:
  Rat   170 VYQQFFAILEANYPETVKNLIVIRAPKLFPVAFNLVKSFIGEVTQKKIVILGGNWK--QELLKFM 232

  Fly   239 PREYLPEEYGGNNGRIADIQAEAEKKLLSYESYFAE-DSQYGVDEQLRP 286
            ..:.||.|:||.   :.|  .:...|.|:..:|..: ...|.:..|.||
  Rat   233 SPDQLPVEFGGT---MTD--PDGNPKCLTKINYGGDVPKHYHLSSQERP 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30339	NP_724813.1	CRAL_TRIO_N	28..70	CDD:215024	13/53 (25%)
CG30339	NP_724813.1	CRAL_TRIO	109..250	CDD:279044	32/150 (21%)
Sec14l4	NP_001102560.1	CRAL_TRIO_N	13..59	CDD:215024	17/63 (27%)
		SEC14	76..244	CDD:214706	41/181 (23%)
		GOLD_2	284..379	CDD:404736
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900