DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30339 and Ku80

DIOPT Version :9

Sequence 1:	NP_724813.1	Gene:	CG30339 / 246549	FlyBaseID:	FBgn0050339	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_609767.2	Gene:	Ku80 / 34930	FlyBaseID:	FBgn0041627	Length:	699	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	67/329 - (20%)
Similarity:	109/329 - (33%)	Gaps:	142/329 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 AETELNEVEERVPA-DLK-ALRDWLAKQPHLRARQDDQFLVGFLRGCKFSLEKTKSKLDHFYTIK 77
            :|.:||.:::.:.: ||: .|||  .:||...|:.|   |:.|
  Fly   420 SEEQLNAIDQLIDSTDLECTLRD--TQQPRPWAQND---LLPF---------------------- 457

  Fly    78 TLMPELFGKRLVD--ERNLILCR------------SGTYVRLPKPWGTDGPRLQLTNYEKFDPKE 128
            ..:|.:|.:.::|  ||.:|...            :..:.|:|.|         |....|.....
  Fly   458 DALPSIFEQNVMDILERKVIYDNDKEDKMLKDKNFADVFWRVPDP---------LEEKSKRAAAI 513

  Fly   129 FKLLDLFRYQTMITEQSIREDDHSNISGYVEIVDMAKMSLSFLAQLDFTLIKRMGIFAEKAQPTR 193
            .|.|...||.....|:.:.::...|                             |: |.|::|..
  Fly   514 VKKLFPLRYSRAWQEKLLAKEQAEN-----------------------------GV-AVKSEPAE 548

  Fly   194 LKGVHLINCPKEGVALLN---------------------------LA---KSLMPSKLQQRFHVY 228
            .:    |..|.:||.|::                           ||   :.::.:.||:|   .
  Fly   549 KE----IPLPSDGVGLIDPISDFRRVLASVHTISNATERDARFQALAADTRVVIITLLQRR---K 606

  Fly   229 KNLEQLNEVIP---------REYLPEEYGGNNGRIADIQAEAEKK--LLSYESYFAEDSQYGVDE 282
            :|:.||.|:|.         ..:|  ||        |..||..||  |....|.|.:|..  ||:
  Fly   607 QNIGQLGELITLYRQSCIDFNTFL--EY--------DKFAEELKKIALAKNRSEFWQDVM--VDK 659

  Fly   283 QLRP 286
            ||.|
  Fly   660 QLGP 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30339	NP_724813.1	CRAL_TRIO_N	28..70	CDD:215024	11/43 (26%)
CG30339	NP_724813.1	CRAL_TRIO	109..250	CDD:279044	30/179 (17%)
Ku80	NP_609767.2	Ku_N	7..213	CDD:281693
		KU80	221..524	CDD:238445	29/139 (21%)
		Ku_PK_bind	562..663	CDD:285938	26/115 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900