DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30339 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_724813.1	Gene:	CG30339 / 246549	FlyBaseID:	FBgn0050339	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001129182.2	Gene:	Sec14l5 / 287060	RGDID:	1564638	Length:	696	Species:	Rattus norvegicus

Alignment Length:	294	Identity:	53/294 - (18%)
Similarity:	107/294 - (36%)	Gaps:	71/294 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LKALRDWLAKQPHLRARQDDQFLVGFLRGCKFSLEKTKSKLDHFYTIKTLMPELFGKRLVDERNL 94
            |..||.|| ::.|......|:.::.|||...|.|:|.:.
  Rat   246 LVQLRRWL-QETHKGKIPKDEHILRFLRARDFHLDKARD-------------------------- 283

  Fly    95 ILCRSGTYVR------LPKPWGTDGPRLQL----TNYEKFDPKEFKLLDLFRYQT-----MITEQ 144
            :||:|.::.:      |.:.|....|..:.    .:|:..|.:...:|.|.:..|     .:.|:
  Rat   284 MLCQSLSWRKQHQVDLLLQTWRPPAPLQEFYAGGWHYQDIDGRPLYILRLGQMDTKGLMKAVGEE 348

  Fly   145 -------SIREDDHSN-----------ISGYVEIVDMAKMSLSFLAQLDFTLIKRMGIFAEKAQP 191
                   |:.|:....           ||.:..::|:..:::..|.:.....:.||....|...|
  Rat   349 ALLQHVLSVNEEGQKRCEGNTRQFGRPISSWTCLLDLEGLNMRHLWRPGVKALLRMIEVVEDNYP 413

  Fly   192 TRLKGVHLINCPKEGVALLNLAKSLMPSKLQQRFHVYKNLEQ-----LNEVIPREYLPEEYGGNN 251
            ..|..:.::..|:....|..|....:....:::|.:|.....     |.:.:.::.:|:..||.:
  Rat   414 ETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKFLIYSGSNYQGPGGLVDYLDKDVIPDFLGGES 478

  Fly   252 GRIADIQAEAEKKLLSYESYFAEDSQYGVDEQLR 285
              :.::   .|..::....|..|:.|...| |||
  Rat   479 --VCNV---PEGGMVPKSLYLTEEEQEQAD-QLR 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30339	NP_724813.1	CRAL_TRIO_N	28..70	CDD:215024	13/39 (33%)
CG30339	NP_724813.1	CRAL_TRIO	109..250	CDD:279044	27/172 (16%)
Sec14l5	NP_001129182.2	PRELI	17..173	CDD:309720
		Amidase	<179..309	CDD:327489	18/89 (20%)
		CRAL_TRIO_N	243..288	CDD:215024	15/68 (22%)
		CRAL_TRIO	314..477	CDD:306996	25/162 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900