DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30339 and ctg-2

DIOPT Version :9

Sequence 1:	NP_724813.1	Gene:	CG30339 / 246549	FlyBaseID:	FBgn0050339	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001254156.1	Gene:	ctg-2 / 174360	WormBaseID:	WBGene00011756	Length:	408	Species:	Caenorhabditis elegans

Alignment Length:	326	Identity:	72/326 - (22%)
Similarity:	114/326 - (34%)	Gaps:	88/326 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LSAELRRIAETELNEVEERVPADLKALRDWLAKQPHLRARQDDQF-----LVGFLR-------GC 59
            ||.|....:..|:.|.:.::   |..||..:.|:..|....||.|     |:|:.|       ..
Worm     8 LSGERMSTSTGEITESDRKL---LDELRKRIHKELELVKEYDDDFSLMRWLIGWDRKIDVVVPKI 69

  Fly    60 KFS----------------LEKTKSKLDH-FYTIKTLMPELFGKRLVDERNLILCRSGTYVRLPK 107
            |||                |||...|.|. ...::.|...|.|   :|..|.:       |.|..
Worm    70 KFSLRAIHALGLDQEDLSTLEKVAQKCDDCSVPLRYLPGSLIG---LDHENNV-------VSLQM 124

  Fly   108 PWGTDGPRLQLTNYEKFDPKEFKLLDLFRYQTMITE---QSIR--EDDHSNISGYVEIVDMAKMS 167
            ....|...|.......         ||:|.:...:|   |.||  |.:.....|...|.|:..:|
Worm   125 IGHLDAAGLMPATRNS---------DLYRMRIAESEGVMQIIRKMEKEQGKPLGTSVIFDLDGLS 180

  Fly   168 LSFLAQLDFTLIKRMGIFAEKAQ---PTRLKGVHLINCPKEGVALLNLAKSLMPSKLQQRFHVYK 229
               :.|:|...:|.:.....:.|   |..::.:.::|.|.....|.::....:..:.||:..:..
Worm   181 ---MVQIDLAALKVVTTMLSQLQEMFPDVIRKIFIVNTPTFIQVLWSMISPCLAKQTQQKVKILG 242

  Fly   230 N--LEQLNEVIPREYLPEEYGGNNGRIADIQAEAEKKLLSYESYFAEDSQYGVDEQLRPGKRVNA 292
            |  .:.|.|.|..|.|.|.:||..      :||.|               ||   .:|.|.::.|
Worm   243 NDWKQHLKENIGEEVLFERWGGTR------KAETE---------------YG---NVRMGGKIPA 283

  Fly   293 D 293
            :
Worm   284 E 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30339	NP_724813.1	CRAL_TRIO_N	28..70	CDD:215024	17/69 (25%)
CG30339	NP_724813.1	CRAL_TRIO	109..250	CDD:279044	32/150 (21%)
ctg-2	NP_001254156.1	SEC14	98..267	CDD:214706	40/196 (20%)
ctg-2	NP_001254156.1	EMP24_GP25L	331..>405	CDD:279450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910