DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30338 and Rwdd2a

DIOPT Version :9

Sequence 1:	NP_724811.1	Gene:	CG30338 / 246548	FlyBaseID:	FBgn0050338	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_001102243.1	Gene:	Rwdd2a / 363110	RGDID:	1306231	Length:	292	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	96/307 - (31%)
Similarity:	149/307 - (48%)	Gaps:	51/307 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EELQTYRRCVGLQLEELELLSSIYCAPGELHMLDAGVVADFNEFLKDDKTKPATSLLSHLEYVVK 68
            |.||       |||.|:|:|.|::...||:.:.|...:.:...:|  |.|:.|  |..::|:|:.
  Rat     7 ESLQ-------LQLLEMEMLFSMFPNQGEVKLEDVNALTNIKRYL--DGTREA--LPPNIEFVIT 60

  Fly    69 LTL-PGKQCVEVRVELPHLYPLLEQARVSVHTTLLGKSKE-----QRLKND-LEQYHGERREEDA 126
            |.: ..|..::::|.:||.||.       |...|.|:|.|     |.|.|. |..|.|  ..:..
  Rat    61 LQIEEPKVTIDLQVTMPHSYPY-------VALQLFGRSPELDRQQQLLLNQGLSAYLG--TFDPG 116

  Fly   127 EPYIFQLLSWLQDRIEDLLKRPASEFEVQQVASSDPQ---QPPATELQRIWIYSHHIKSSAKRQE 188
            |..:...:.||||.        ::.:.:.:..|.:|.   :|......|:|||||||.....|::
  Rat   117 ELCVCAAIQWLQDN--------SASYFLNRKLSDEPSVQPKPVKNTFLRMWIYSHHIYQQDLRKK 173

  Fly   189 LIRQARQLELTGFSRPGKPGIICVEGDSANVQEFWRTIKALRWQKISVVRTEPRQRK------RG 247
            ::...::|::|||...||||||||||...:.:|||.||:...|:.||....|..:.:      |.
  Rat   174 ILEVGKRLDVTGFCMTGKPGIICVEGFKDHCEEFWHTIRYPNWKHISCKHAETVETEGDGEDLRL 238

  Fly   248 FEDFSEQLFNA--EEGV-----MNMGQFIRFLEAHGFGYMKSELFGL 287
            |..|.|.|..|  :.|:     ||:|||:.||..|...::...|||:
  Rat   239 FHSFEELLLEAHGDYGLRNDYHMNLGQFLEFLRKHKSEHVFQILFGI 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30338	NP_724811.1	DUF1115	175..>240	CDD:284060	29/64 (45%)
Rwdd2a	NP_001102243.1	RWD	15..134	CDD:413438	37/139 (27%)
Rwdd2a	NP_001102243.1	DUF1115	160..281	CDD:399506	45/120 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335164
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28IR6
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12315
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4503
OMA	1	1.010	-	-		QHG53050
OrthoDB	1	1.010	-	-		D1387276at2759
OrthoFinder	1	1.000	-	-		FOG0004978
OrthoInspector	1	1.000	-	-		otm45299
orthoMCL	1	0.900	-	-		OOG6_103700
Panther	1	1.100	-	-	O	PTHR15955
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3514
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.810