Protein Alignment Vha100-3 and STV1

DIOPT Version :9

• Sequence 1: NP_725837.1
• Gene: Vha100-3 / 246543
• FlyBaseID: FBgn0028669
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_013770.1
• Gene: STV1 / 855076
• SGDID: S000004658
• Length: 890
• Species: Saccharomyces cerevisiae
• Alignment Length: 981
• Identity: 276/981 - (28%)
• Similarity: 438/981 - (44%)
• Gaps: 195/981 - (19%)

  Fly    12 KSFFRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYELLRIVD 76
            ::.|||.||...||.:..|...:....:|........::..:.......|..::.:..|:.|:|.
Yeast     5 EAIFRSADMTYVQLYIPLEVIREVTFLLGKMSVFMVMDLNKDLTAFQRGYVNQLRRFDEVERMVG 69

  Fly    77 SLH---------TYIVQLHV----NEIFYPDV-DRENRLKEKDLAKYSDSLKRI---HVEASAVT 124
            .|:         |:...||:    |:|..||: |..|.::...|...:|.:|.|   ...|..:.
Yeast    70 FLNEVVEKHAAETWKYILHIDDEGNDIAQPDMADLINTMEPLSLENVNDMVKEITDCESRARQLD 134

  Fly   125 EHYYRLDSRRNRMMEHSFALNKANKYM-----------------------------------VSD 154
            |....|.|:.|.::|....:.:.:|::                                   :||
Yeast   135 ESLDSLRSKLNDLLEQRQVIFECSKFIEVNPGIAGRATNPEIEQEERDVDEFRMTPDDISETLSD 199

  Fly   155 --------------MGSELLYSESTVIGLVQDATTTSGAYPAHLNYMI-GCIRADKFYSFELLLY 204
                          :|::|..::|     |:|.:.....| .| .||| |.||..|......:|:
Yeast   200 AFSFDDETPQDRGALGNDLTRNQS-----VEDLSFLEQGY-QH-RYMITGSIRRTKVDILNRILW 257

  Fly   205 RLCSFNLIIRFSEMPSPVYEYHYGYKPERVRKFAILMMASSTMIWPKVLKICAHYHVNIYDCPSS 269
            ||...|||.:...:..|:.|     ..|:|.|...::......:..||.::....:..|....:.
Yeast   258 RLLRGNLIFQNFPIEEPLLE-----GKEKVEKDCFIIFTHGETLLKKVKRVIDSLNGKIVSLNTR 317

  Fly   270 ASQREDKVKELSQEIVNVEKVLKEAELMRRQILEVAGRDLFIIRVNLRKALKVYDLMNRLRLVGG 334
            :|:..|   .|:::|.:::::|...|......|.|....|.:.....::...||..:|:.:
Yeast   318 SSELVD---TLNRQIDDLQRILDTTEQTLHTELLVIHDQLPVWSAMTKREKYVYTTLNKFQ---- 375

  Fly   335 VEVPRYLLAEVYIPSSDVPEVEVILRNASRISGGADNIDSSDEDEMNDMKTMPNTTPYPIEADFQ 399
             :..:.|:||.::||:::..::             |::....|...::..|:.|..
Yeast   376 -QESQGLIAEGWVPSTELIHLQ-------------DSLKDYIETLGSEYSTVFNVI--------- 417

  Fly   400 PLEDMSAGAILLKKNRLVNHMPPTYFRLNKFTRGFQNLIDAYGMADYKELNPAPYTIITFPFLFA 464
                            |.|.:||||.|.||||:.||:::||||:|.|||:|....|::||||:||
Yeast   418 ----------------LTNKLPPTYHRTNKFTQAFQSIVDAYGIATYKEINAGLATVVTFPFMFA 466

  Fly   465 VMFGDLGHGILLILFSSLMIWKHREIEKYQINATSENEILNILYAGRYIILLMGVFSVYMGLVYN 529
            :||||:|||.:|.|.:..::...|     :..|...:||.::.:.|||::||||.||||.||:||
Yeast   467 IMFGDMGHGFILFLMALFLVLNER-----KFGAMHRDEIFDMAFTGRYVLLLMGAFSVYTGLLYN 526

  Fly   530 IVMAKGFNLFGSSW----------SCRYNETTVYDPAFHVTLDSSHPHFYSGHPYPLGMDPVWAV 584
            .:.:|...:|.|.|          |....:|.|                     ||.|:|..|.
Yeast   527 DIFSKSMTIFKSGWQWPSTFRKGESIEAKKTGV---------------------YPFGLDFAWH- 569

  Fly   585 CGQDS-ITTTNSLKMKMAIVLGISQMMFGLGLAAANCVLMNRKADLILVVIPQMIFMLCLFGYLV 648
             |.|: :..:||.|||::|::|.:.|.:....:..|....|.|.|:|...||.::||..:||||.
Yeast   570 -GTDNGLLFSNSYKMKLSILMGYAHMTYSFMFSYINYRAKNSKVDIIGNFIPGLVFMQSIFGYLS 633

  Fly   649 FLIFYKWMS--YGGHKPAPYNAACAPSVLITFINMMLMKKEDPVENCLDYMYPNERMIEFALVGI 711
            :.|.|||..  ....||       ||.:|...|||.|  ....::   |.:|..:..::..|:..
Yeast   634 WAIVYKWSKDWIKDDKP-------APGLLNMLINMFL--APGTID---DQLYSGQAKLQVVLLLA 686

  Fly   712 AFCTIPILLAGKPIYLMRRRRKMQQERERDFKRM----RRQTIAEMRST------MRYTDDDNSE 766
            |...:|.||..||:.|.|..:.....|...::.:    ..:.||:.|.:      |..:|..:..
Yeast   687 ALVCVPWLLLYKPLTLRRLNKNGGGGRPHGYQSVGNIEHEEQIAQQRHSAEGFQGMIISDVASVA 751

  Fly   767 TSRQKSVDNEEE--HEMSEIWIHSGIHTIETVLGSVSHTASYLRLWALSLAHDQLSDVLWHMVLT 829
            .|..:||...|:  ....::.||..|||||..|..:||||||||||||||||.|||.|||.|.::
Yeast   752 DSINESVGGGEQGPFNFGDVMIHQVIHTIEFCLNCISHTASYLRLWALSLAHAQLSSVLWDMTIS 816

  Fly   830 KGFANT---LPLYYGVPVLMATFFAWAILTVAILVMMEGLSAFLHTLRLHWVEFQSKFFGGAGES 891
            ..|::.   .||  .|..::..|..|.:|||.|||.|||.||.||.|||||||..||||.|.|.:
Yeast   817 NAFSSKNSGSPL--AVMKVVFLFAMWFVLTVCILVFMEGTSAMLHALRLHWVEAMSKFFEGEGYA 879

  Fly   892 FKAFNF 897
            ::.|:|
Yeast   880 YEPFSF 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-3	NP_725837.1	V_ATPase_I	38..897	CDD:279793	267/953 (28%)
STV1	NP_013770.1	V_ATPase_I	32..885	CDD:396194	267/952 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344197
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1269
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S598
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000328
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100301
Panther	1	1.100	-	-	O	PTHR11629
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.650