Protein Alignment Vha100-3 and atp6v0a2

DIOPT Version :9

• Sequence 1: NP_725837.1
• Gene: Vha100-3 / 246543
• FlyBaseID: FBgn0028669
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_001016223.1
• Gene: atp6v0a2 / 548977
• XenbaseID: XB-GENE-960957
• Length: 845
• Species: Xenopus tropicalis
• Alignment Length: 913
• Identity: 321/913 - (35%)
• Similarity: 498/913 - (54%)
• Gaps: 105/913 - (11%)

  Fly    13 SFFRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYELLRIVDS 77
            ||||||.|.|.||.|.:.:|:||:.|:|..|..:|.::..:.......:..:|.:|.|:.||:..
 Frog     3 SFFRSEAMCLAQLFLQSGSAYDCVSELGEMGLAEFRDLNPQVSAFQRKFVGEVKKCEEMERILGY 67

  Fly    78 LHTYIVQLHVNEIFYPDVDRENRLKEKDLAKY----SDSLKRIHVEASAVTEHYYRLDSRRNRMM 138
            |...|.:.::      .|..|:...|..|.|:    .:.|:::.||...|.::..:|......|:
 Frog    68 LMQEIQKANI------PVPEESLTPEAPLPKHVLDIQEQLQKLEVELREVNKNKEKLQKNLLEMI 126

  Fly   139 EHSFALNKANKYMV-----SDMGSELLYSESTVI---GLVQDATTTSGAYPAHLNYMIGCIRADK 195
            |:::.|...| |:|     .:..:...|.|...:   .|:.  .|......|.|.::.|.:...|
 Frog   127 EYTYMLRVTN-YLVHRSNEHETSAHSTYEEFPALEKESLID--YTCMQRLGAKLGFVSGLVHRAK 188

  Fly   196 FYSFELLLYRLCSFNLIIRFSEMPSPVYEYHYGYKPERVRKFAILMMASSTMIWPKVLKICAHYH 260
            ..|||.:|:|:|....::.:.|:..  |..|...: |..|.|..::......|..||.|||..|.
 Frog   189 LESFEKMLWRVCKGYTVLTYQELDE--YLLHPDTE-EPTRWFVFVVSYWGDQIGQKVKKICECYD 250

  Fly   261 VNIYDCPSSASQREDKVKELSQEIVNVEKVLKEAELMRRQILEVAGRDLFIIRVNLRKALKVYDL 325
            .::|...:||.:|.:.:.||:..|.::.||:.:.:...:|:|..|...::...:.::|...:|.:
 Frog   251 CHLYPYTNSAEERRNLLSELNTRIQDLHKVISQTDDYLKQVLFKASESVYKWVIQIKKMKAIYHV 315

  Fly   326 MNRLRLVGGVEVP-RYLLAEVYIPSSDVPEVEVILRNASRISGGADNIDSSDEDEMNDMKTMPNT 389
            :|..|.    :|. :.|:|||:.|.:|:|.|...|...||.||
 Frog   316 LNFCRF----DVTNKCLIAEVWCPVADLPNVRRALEEGSRKSG---------------------- 354

  Fly   390 TPYPIEADFQPLEDMSAGAILLKKNRL-VNHMPPTYFRLNKFTRGFQNLIDAYGMADYKELNPAP 453
                          :|..:.:   ||: .|..|||..|.||||.||||::||||:.:|:|:||||
 Frog   355 --------------VSVPSFI---NRIPSNDTPPTLIRTNKFTSGFQNIVDAYGVGNYREMNPAP 402

  Fly   454 YTIITFPFLFAVMFGDLGHGILLILFSSLMIWKHREIEKYQINATSENEILNILYAGRYIILLMG 518
            ||||||||||||||||.|||||:.||:..|:    ..||....|.|::||:...:.|||||||||
 Frog   403 YTIITFPFLFAVMFGDFGHGILMSLFALCMV----VFEKSPKLARSQDEIMKTFFEGRYIILLMG 463

  Fly   519 VFSVYMGLVYNIVMAKGFNLFGSSWSCRYNETTVYDPAFHVTLDSSHPHFYSGHP---------Y 574
            :||:|.||:||...:|..|:|||||    |.:.::......|.|.|: .|.:.:|         |
 Frog   464 LFSIYTGLIYNDCFSKSMNIFGSSW----NVSAMFSSNVWRTQDLSN-KFLTLNPNVTGVLTGVY 523

  Fly   575 PLGMDPVWAVCGQDSITTTNSLKMKMAIVLGISQMMFGLGLAAANCVLMNRKADLILVVIPQMIF 639
            |:|:||:|:: ..:.::..||.||||:::||:..|.||:.|:|.|.:...::..:.||.||:::|
 Frog   524 PVGIDPIWSL-STNRLSFLNSFKMKMSVILGVIHMTFGVVLSAFNYMHFKKRFCIFLVFIPELLF 587

  Fly   640 MLCLFGYLVFLIFYKWMSYGGHKPAPYNAACAPSVLITFINMMLMKKEDPVENCLDYMYPNERMI 704
            |:|:||||||:|.|||::|     :..::..|||:|:.||||.:..|.|.:    ..::..:..|
 Frog   588 MICIFGYLVFMILYKWLAY-----SAADSRNAPSILLHFINMFMFSKNDQI----PALFTGQVGI 643

  Fly   705 EFALVGIAFCTIPILLAGKPIYLMRRRRKMQQER--ERDFKRMRRQTIAEMRSTMRYTDDDNSET 767
            :..|:.:....:|:||.|||:||..:....|..|  .:.:..:||.:..|: |.:|..|.:..|.
 Frog   644 QIFLIVLVTLCVPVLLFGKPLYLYWQHHGGQTLRNYRKGYTLVRRGSEEEI-SLVRSHDLEEGEI 707

  Fly   768 SRQKSVD---NEEEHEMSEIWIHSGIHTIETVLGSVSHTASYLRLWALSLAHDQLSDVLWHMVLT 829
            :....|.   ::|:.:.:::::...|||||..||.:|:||.|||||||||||.|||:|||.|::.
 Frog   708 NSSHEVQRDRDKEKFDFADVFMSQAIHTIEYCLGCISNTALYLRLWALSLAHAQLSEVLWGMIMR 772

  Fly   830 KGFANTLPLYYGVPVLMATFFAWAILTVAILVMMEGLSAFLHTLRLHWVEFQSKFFGGAGESFKA 894
            ||. |..| ..||.||:..|..:|.||:|||::|||||||||.|||||||||:||:.|||..|..
 Frog   773 KGL-NVEP-SVGVFVLIPLFAVFAFLTIAILLVMEGLSAFLHALRLHWVEFQNKFYTGAGYKFNP 835

  Fly   895 FNF 897
            |:|
 Frog   836 FSF 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-3	NP_725837.1	V_ATPase_I	38..897	CDD:279793	306/886 (35%)
atp6v0a2	NP_001016223.1	NtpI	27..839	CDD:224188	307/889 (35%)
		V_ATPase_I	28..838	CDD:279793	306/886 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D164762at33208
OrthoFinder	1	1.000	-	-		FOG0000328
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11629
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110